Vibrissa motor cortex activity suppresses contralateral whisking behavior.
Vibrissa motor cortex activity suppresses contralateral whisking behavior.
复制标题
Vibrissa运动皮层活性抑制对侧搅拌行为。
DOI:
10.1038/nn.4437
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发表时间:
2017-01
影响因子:
25
通讯作者:
Brecht M
中科院分区:
文献类型:
--
作者:
Ebbesen CL;Doron G;Lenschow C;Brecht M
Anatomical, stimulation and lesion data implicate vibrissa motor cortex in whisker motor control. Work on motor cortex focused on movement generation, but correlations between vibrissa motor cortex activity and whisking are weak. The exact role of vibrissa motor cortex remains unknown. We recorded vibrissa motor cortex neurons during various forms of vibrissal touch, which were invariably associated with whisker protraction and movement. Free whisking, object palpation and social touch all resulted in decreased cortical activity. To understand this activity decrease, we performed juxtacellular recordings, nanostimulation and in vivo whole-cell-recordings. Social facial touch resulted in decreased spiking activity, decreased cell excitability and membrane hyperpolarization. Activation of vibrissa motor cortex by intra-cortical microstimulation elicited whisker retraction, as if to abort vibrissal touch. Various vibrissa motor cortex inactivation protocols resulted in contralateral protraction and increased whisker movements. These data collectively point to movement suppression as a prime function of vibrissa motor cortex activity.
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DOI:
10.1111/j.1460-9568.2009.07067.x
发表时间:
2010-01
期刊:
The European journal of neuroscience
影响因子:
--
作者:
Dushanova J;Donoghue J
通讯作者:
Donoghue J
影响因子:
16.2
作者:
Deschênes M;Takatoh J;Kurnikova A;Moore JD;Demers M;Elbaz M;Furuta T;Wang F;Kleinfeld D
通讯作者:
Kleinfeld D
影响因子:
16.2
作者:
Hill DN;Curtis JC;Moore JD;Kleinfeld D
通讯作者:
Kleinfeld D
影响因子:
2.9
作者:
GIOANNI, Y;LAMARCHE, M
通讯作者:
LAMARCHE, M
影响因子:
5.3
作者:
Haiss, F;Schwarz, C
通讯作者:
Schwarz, C