Sound localization of world and head-centered space in ferrets
Sound localization of world and head-centered space in ferrets
复制标题
雪貂世界和头部中心空间的声音定位
DOI：
10.1101/2021.09.15.460425
复制
发表时间：
2021
期刊：
影响因子：
--
通讯作者：
Town S
中科院分区：
文献类型：
--
作者：
Town S
声音的位置可以在多个坐标系中描述，这些坐标系相对于我们自己或我们周围的世界定义。来自动物神经记录的证据表明，大脑中既存在以头部为中心的声音位置表征，也有以世界为中心的声音位置表征；然而，尚不清楚这种神经表征是否与非人类听者的声音定位能力具有知觉相关性。在这里，我们建立了新的行为测试来确定雪貂能够定位声音的坐标系。我们发现，雪貂可以学会区分固定在以世界为中心或以头部为中心的空间中的声音位置，跨越不同坐标系中声音位置的巨大变化。使用探测声来评估更广泛的空间听力泛化，我们证明了在头部和以世界为中心的任务中，动物使用连续的听觉空间地图来指导行为。单个动物的单次试验反应提供了足够的信息，因此我们可以使用特定坐标系中的说话者位置来建模声音定位，并在保持的数据中准确地预测雪貂的行动。我们的结果表明，雪貂是一种动物模型，在这种动物模型中，神经元被调谐到以自我为中心和以分配为中心的参照系中的声音位置，也可以在多个头部和以世界为中心的空间中定位声音。这些不同的空间也体现在动物神经元的活动中，但目前还不清楚非人类的听者是否也感知到以头部和世界为中心的声音位置。在这里，我们设计了行为任务，让雪貂根据它们在世界上的位置或相对于头部的位置来区分声音。受试者学会了解决问题，并学会了在每个空间听到不常见的探测声音时概括出声音的位置。这些发现揭示了以前在雪貂大脑中观察到的神经敏感性的知觉关联，并确立了雪貂和人类一样，可以访问他们当地环境的听觉地图。
The location of sounds can be described in multiple coordinate systems that are defined relative to ourselves, or the world around us. Evidence from neural recordings in animals point toward the existence of both head-centered and world-centered representations of sound location in the brain; however, it is unclear whether such neural representations have perceptual correlates in the sound localization abilities of nonhuman listeners. Here, we establish novel behavioral tests to determine the coordinate systems in which ferrets can localize sounds. We found that ferrets could learn to discriminate between sound locations that were fixed in either world-centered or head-centered space, across wide variations in sound location in the alternative coordinate system. Using probe sounds to assess broader generalization of spatial hearing, we demonstrated that in both head and world-centered tasks, animals used continuous maps of auditory space to guide behavior. Single trial responses of individual animals were sufficiently informative that we could then model sound localization using speaker position in specific coordinate systems and accurately predict ferrets' actions in held-out data. Our results demonstrate that ferrets, an animal model in which neurons are known to be tuned to sound location in egocentric and allocentric reference frames, can also localize sounds in multiple head and world-centered spaces.SIGNIFICANCE STATEMENTHumans can describe the location of sounds either relative to themselves, or in the world, independent of their momentary position. These different spaces are also represented in the activity of neurons in animals, but it is not clear whether nonhuman listeners also perceive both head and world-centered sound location. Here, we designed behavioral tasks in which ferrets discriminated between sounds using their position in the world, or relative to the head. Subjects learnt to solve both problems and generalized sound location in each space when presented with infrequent probe sounds. These findings reveal a perceptual correlate of neural sensitivity previously observed in the ferret brain and establish that, like humans, ferrets can access an auditory map of their local environment.
登录
查看更多内容
影响因子：
25
作者：
Keating, Peter;Dahmen, Johannes C.;King, Andrew J.
通讯作者：
King, Andrew J.
猫的动态声音定位。
影响因子：
2.5
作者：
Ruhland,JanetL;Jones,AmyE;Yin,TomCT
通讯作者：
Yin,TomCT
影响因子：
25
作者：
Mathis, Alexander;Mamidanna, Pranav;Bethge, Matthias
通讯作者：
Bethge, Matthias
初级听觉皮层中的神经元以线索不变的方式表示声源位置
影响因子：
16.6
作者：
Katherine C. Wood;S. M. Town;J. Bizley
通讯作者：
J. Bizley
DOI：
10.1523/jneurosci.07-07-01951.1987
发表时间：
1987-07
期刊：
--
影响因子：
--
作者：
R. Muller;J. Kubie
通讯作者：
R. Muller;J. Kubie