Initial clinical experience with a radiation oncology dedicated open 1.0T MR-simulation.
Initial clinical experience with a radiation oncology dedicated open 1.0T MR-simulation.
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DOI：
10.1120/jacmp.v16i2.5201
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发表时间：
2015-03-08
影响因子：
2.1
通讯作者：
Siddiqui MS
中科院分区：
文献类型：
--
作者：
Glide-Hurst CK;Wen N;Hearshen D;Kim J;Pantelic M;Zhao B;Mancell T;Levin K;Movsas B;Chetty IJ;Siddiqui MS
这项研究的目的是描述我们使用1.0T MR-SIM的经验，包括特征、质量保证(QA)计划和治疗计划所必需的特征。制定了人员配备、安全和患者筛查程序。说明了外部激光定位系统(ELPS)和MR兼容沙发的使用。在CT-SIM和MR-SIM之间使用具有已知标志和体积的立体定向QA体模进行空间和体积分析。用相位差分析确定了磁场的不均匀性。评估系统相关的平面内失真，并评估时间变化。对远离等中心的感兴趣区(ROI)的三维变形进行了表征。分析了美国放射学会(ACR)推荐的检查方法和ELPS对图像质量的影响。评价联合超短回波时间Dixon(UTE/Dixon)序列。使用一个运动体模(2-10个时相，漂移，3-5个S周期)和一个肝癌患者进行幅度触发的4D磁共振成像。在最大强度投影(MIP)数据集之间评估占空比、采集时间和漂移。CT-SIM和MR-SIM体积之间的平均距离与预期相差不到2%。磁场的不均匀性是。二维变形超过等中心。在等中心半径5 cm范围内，平均三维几何变形为()，且从等中心(，)开始增大。ELPS干扰在扫描仪的工作频率范围内，以线条图案和信噪比降低(4.6-12.6%)为特征。图像质量检查符合ACR建议。UTE/Dixon序列在骨骼和空气之间产生了可检测性。在4DMRI中，快呼吸周期的占空比高于慢呼吸周期(50.4%(3位S)和39.4%(5位S))，10相的采集时间比两相增加4倍。与十相MIP相比，两相MIP的上下对象范围被低估了8%(6 Mm)，尽管不同阶段的MIP有所不同。一名患者的4D MRI显示图像质量可接受。MR-SIM被整合到我们的工作流程中，并开发了质量保证程序。4D MRI和UTE成像的临床适用性被证明，以支持MR-SIM用于单一模式的治疗计划。PAC编号：87.56.fc，87.61.-c，87.57.cp
The purpose of this study was to describe our experience with 1.0T MR‐SIM including characterization, quality assurance (QA) program, and features necessary for treatment planning. Staffing, safety, and patient screening procedures were developed. Utilization of an external laser positioning system (ELPS) and MR‐compatible couchtop were illustrated. Spatial and volumetric analyses were conducted between CT‐SIM and MR‐SIM using a stereotactic QA phantom with known landmarks and volumes. Magnetic field inhomogeneity was determined using phase difference analysis. System‐related, in‐plane distortion was evaluated and temporal changes were assessed. 3D distortion was characterized for regions of interest (ROIs) away from isocenter. American College of Radiology (ACR) recommended tests and impact of ELPS on image quality were analyzed. Combined ultrashort echotime Dixon (UTE/Dixon) sequence was evaluated. Amplitude‐triggered 4D MRI was implemented using a motion phantom (2–10 phases, excursion, 3–5 s periods) and a liver cancer patient. Duty cycle, acquisition time, and excursion were evaluated between maximum intensity projection (MIP) datasets. Less than 2% difference from expected was obtained between CT‐SIM and MR‐SIM volumes, with a mean distance of between landmarks. Magnetic field inhomogeneity was . 2D distortion was over of isocenter. Within 5 cm radius of isocenter, mean 3D geometric distortion was () and increased from isocenter (, ). ELPS interference was within the operating frequency of the scanner and was characterized by line patterns and a reduction in signal‐to‐noise ratio (4.6–12.6% for ). Image quality checks were within ACR recommendations. UTE/Dixon sequences yielded detectability between bone and air. For 4D MRI, faster breathing periods had higher duty cycles than slow (50.4% (3 s) and 39.4% (5 s), ) and ~ fourfold acquisition time increase was measured for ten‐phase versus two‐phase. Superior–inferior object extent was underestimated 8% (6 mm) for two‐phase as compared to ten‐phase MIPs, although difference was obtained for phases. 4D MRI for a patient demonstrated acceptable image quality in . MR‐SIM was integrated into our workflow and QA procedures were developed. Clinical applicability was demonstrated for 4D MRI and UTE imaging to support MR‐SIM for single modality treatment planning. PACS numbers: 87.56.Fc, 87.61.‐c, 87.57.cp
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影响因子：
3.8
作者：
Adamson, Justus;Chang, Zheng;Cai, Jing
通讯作者：
Cai, Jing
影响因子：
3.3
作者：
Cao, Junsheng;Cui, Yunfeng;Yu, Yan
通讯作者：
Yu, Yan
影响因子：
5
作者：
Kanal, E;Borgstede, JP;Zinninger, MD
通讯作者：
Zinninger, MD
DOI：
10.1016/j.ijrobp.2012.12.014
发表时间：
2013-05-01
影响因子：
7
作者：
Hu, Yanle;Caruthers, Shelton D.;Low, Daniel A.;Parikh, Parag J.;Mutic, Sasa
通讯作者：
Mutic, Sasa
影响因子：
3.8
作者：
Johansson, Adam;Karlsson, Mikael;Nyholm, Tufve
通讯作者：
Nyholm, Tufve