Hyperlipidemia in patients with periodontitis.

Hyperlipidemia in patients with periodontitis.
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牙周炎患者的高脂血症。

DOI:
10.5005/jcdp-6-3-78
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发表时间:
2005
期刊:
The journal of contemporary dental practice
影响因子:
--
通讯作者:
I. Tabatabaie
I. Tabatabaie
中科院分区:
--
文献类型:
--
作者:
A. Moeintaghavi;A. Haerian;M. Talebi;I. Tabatabaie

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背景 牙周炎是一种细菌性感染,已被列为局部慢性炎症。这与心血管疾病一样,可能有共同的风险因素,如吸烟,糖尿病,行为因素,衰老和男性性别。本研究的目的是评估高脂血症和牙周炎之间的关系。 材料和方法 对40例平均年龄为32.3 ± 1.2岁的牙周炎患者(CPITN评分为III或IV,牙周袋深度为4 mm)的血脂水平进行了测定,并与40例年龄和性别匹配的对照组进行了比较。根据病史,两组患者均全身健康。 结果 病例组的总胆固醇(CHL)和甘油三酯(TG)显著升高(分别为P=0.045和P=0.016)。高密度脂蛋白和低密度脂蛋白胆固醇较高的患者,但没有任何显着差异与控制。病例组TG和CHL病理值出现的频率明显高于对照组。 结论 提示高脂血症可能与健康人牙周炎有关。然而,目前尚不清楚牙周炎是否会导致血脂水平升高,或者高脂血症是否是牙周炎和心血管疾病的危险因素。
BACKGROUND Periodontitis is a bacterial infection, which has been classified as a local chronic inflammation. This, as well as cardiovascular disease, may share common risk factors such as smoking, diabetes, behavioral factors, aging, and male gender. The aim of this study was to evaluate the association between hyperlipidemia and periodontitis. MATERIALS AND METHODS The levels of plasma lipids in 40 subjects with periodontitis (CPITN score III or IV, pocket depth 4 mm) with mean age 32.3 +/-1.2 years were measured and compared with those obtained from 40 age and sex matched controls. Both groups were systemically healthy according to their medical history. RESULTS Total cholesterol (CHL) and triglycerides (TG) were significantly higher in the case group (P=0.045 and P=0.016, respectively). HDL and LDL cholesterols were higher in patients but did not have any significant differences with controls. The frequency of persons with pathologic values of TG and CHL were significantly higher in cases compared with controls. CONCLUSIONS These results showed hyperlipidemia may be associated with periodontitis in healthy people. However, it is unclear whether periodontitis causes an increase in levels of serum lipids or hyperlipidemia is a risk factor for both periodontitis and cardiovascular disease.
DOI: 10.2337/diab.40.10.1228
发表时间: 1991-10
期刊: Diabetes
影响因子: 7.7
作者:
G. Divertie;M. Jensen;J. Miles
通讯作者: G. Divertie;M. Jensen;J. Miles
DOI: --
发表时间: 1989-04
影响因子: 6.5
作者:
Carl Grunfeld;R. Gulli;A. Moser;L. Gavin;K. Feingold
通讯作者: Carl Grunfeld;R. Gulli;A. Moser;L. Gavin;K. Feingold
老年人牙周病、内科疾病和免疫力之间的相互作用。
DOI: 10.1111/j.1600-0757.1998.tb00117.x
发表时间: 1998
期刊: Periodontology 2000.
影响因子: --
作者:
Loesche,WJ;Lopatin,DE
通讯作者: Lopatin,DE
DOI: 10.1172/jci113046
发表时间: 1987-07-01
影响因子: 15.9
作者:
FEINGOLD, KR;GRUNFELD, C
通讯作者: GRUNFELD, C