Vaccines for Venezuelan equine encephalitis.
Vaccines for Venezuelan equine encephalitis.
复制标题
委内瑞拉马脑炎的疫苗。
DOI：
10.1016/j.vaccine.2009.07.095
复制
发表时间：
2009-11-05
期刊：
影响因子：
5.5
通讯作者：
Weaver SC
中科院分区：
文献类型：
--
作者：
Paessler S;Weaver SC
Arboviruses are capable of causing encephalitis in animals and human population when transmitted by the vector or potentially via infectious aerosol. Recent re-emergence of Venezuelan equine encephalitis virus (VEEV) in South America emphasizes the importance of this pathogen to public health and veterinary medicine. Despite its importance no antivirals or vaccines against VEEV are currently available in the USA. Here we review some of the older and newer approaches aimed at generating a safe and immunogenic vaccine as well as most recent data about the mechanistic of protection in animal models of infection.
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