V-shaped ion funnel proton transfer reaction mass spectrometry

V-shaped ion funnel proton transfer reaction mass spectrometry
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V型离子漏斗质子转移反应质谱分析

DOI:
10.1080/10739149.2019.1579100
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发表时间:
2019-03
影响因子:
1.6
通讯作者:
Yannan Chu
Yannan Chu
中科院分区:
工程技术4区
文献类型:
--
作者:
Yuejie Wang;Kexiu Dong;Yannan Chu

文献摘要

参考文献

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摘要研制了一种用于质子转移反应质谱(PTR-MS)的V型离子漏斗(IF)漂移管。的离子传输的特点是在可变的射频电压和频率,以获得优化的条件,同时考虑径向聚焦,反应速率和碰撞诱导解离的影响。通过实验获得了对常见化合物的灵敏度提高,根据分析物的不同,灵敏度提高了2至22倍。结合文献报道的U型IF PTR-MS,为IF PTR-MS和其他质谱仪的优化提供了有价值的参考。
Abstract A V-shaped ion funnel (IF) drift tube was developed for proton transfer reaction mass spectrometry (PTR-MS). The ion transmissions were characterized at variable radio frequency voltages and frequencies to obtain optimized conditions while considering the effects of radial-focusing, reaction rate, and collision-induced dissociation. The improvements in sensitivity for common compounds were experimentally obtained and ranges from 2 to 22 times depending on the analyte. The product ions distributions were also studied for V-shaped IF PTR-MS. Together with the literature reports for U-shaped IF PTR-MS, a valuable and comprehensive reference is provided for future optimization of IF PTR-MS and other mass spectrometers.
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