New insights into Rho signaling from plant ROP/Rac GTPases.
New insights into Rho signaling from plant ROP/Rac GTPases.
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DOI:
10.1016/j.tcb.2012.05.002
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发表时间:
2012-09
影响因子:
19
通讯作者:
Yang Z
中科院分区:
文献类型:
--
作者:
Craddock C;Lavagi I;Yang Z
In animal and plant cells, a wide range of key cellular processes that require the establishment of cell polarity are governed by Rho-GTPases. In contrast to animals and yeast, however, plants possess a single Rho-GTPase subfamily called ROP (Rho-like GTPases from plants). This raises the question of how plants achieve the high level of regulation required for polar cellular processes. It is becoming evident that plants have evolved specific regulators, including ROP-Guanine Exchange Factors (GEFs) and the Rop-interactive CRIB motif–containing proteins (RIC) effectors. Recent research shows that the spatiotemporal dynamics of ROPs, the cytoskeleton, endocytosis and exocytosis are intertwined. This review focuses on the proposed self-organizing nature of ROPs in plants and how ROP-mediated cellular mechanisms compare with those responsible for cell polarity in animals and yeast.
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DOI:
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发表时间:
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期刊:
Current biology : CB
影响因子:
--
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