Bovine cryptosporidiosis: impact, host-parasite interaction and control strategies.
Bovine cryptosporidiosis: impact, host-parasite interaction and control strategies.
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DOI：
10.1186/s13567-017-0447-0
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发表时间：
2017-08-11
影响因子：
4.4
通讯作者：
Innes EA
中科院分区：
文献类型：
--
作者：
Thomson S;Hamilton CA;Hope JC;Katzer F;Mabbott NA;Morrison LJ;Innes EA
由顶复门寄生虫隐孢子虫引起的胃肠道疾病是幼龄反刍家畜，特别是新生小牛的最重要疾病之一。受感染的动物可能会出现大量水样腹泻、脱水，严重时可能会死亡。目前，还没有有效的治疗和预防措施，需要更好地了解宿主-病原体相互作用。隐孢子虫也是一种重要的人畜共患病原体，可导致严重的人类疾病，幼儿尤其容易受到感染。隐孢子虫寄生虫在临床相关宿主中诱导的免疫应答我们的知识是非常有限的。本文综述了牛隐孢子虫病的影响，并介绍了如何彻底了解宿主-病原体相互作用可能有助于确定新的预防和控制策略。
Gastrointestinal disease caused by the apicomplexan parasite Cryptosporidium parvum is one of the most important diseases of young ruminant livestock, particularly neonatal calves. Infected animals may suffer from profuse watery diarrhoea, dehydration and in severe cases death can occur. At present, effective therapeutic and preventative measures are not available and a better understanding of the host–pathogen interactions is required. Cryptosporidium parvum is also an important zoonotic pathogen causing severe disease in people, with young children being particularly vulnerable. Our knowledge of the immune responses induced by Cryptosporidium parasites in clinically relevant hosts is very limited. This review discusses the impact of bovine cryptosporidiosis and describes how a thorough understanding of the host–pathogen interactions may help to identify novel prevention and control strategies.
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影响因子：
64.8
作者：
Cella, Marina;Fuchs, Anja;Vermi, William;Facchetti, Fabio;Otero, Karel;Lennerz, Jochen K. M.;Doherty, Jason M.;Mills, Jason C.;Colonna, Marco
通讯作者：
Colonna, Marco
影响因子：
1.3
作者：
Canals, A;Pasquali, P;Gasbarre, LC
通讯作者：
Gasbarre, LC
影响因子：
3.1
作者：
Abrahamsen, MS;Lancto, CA;Jutila, MA
通讯作者：
Jutila, MA
影响因子：
4.4
作者：
Bedi, Brahmchetna;McNair, Nina N.;Mead, Jan R.
通讯作者：
Mead, Jan R.
DOI：
10.1016/j.cvfa.2012.07.002
发表时间：
2012-11
期刊：
The Veterinary clinics of North America. Food animal practice
影响因子：
--
作者：
Blanchard PC
通讯作者：
Blanchard PC