MEG/EEG source reconstruction, statistical evaluation, and visualization with NUTMEG.

MEG/EEG source reconstruction, statistical evaluation, and visualization with NUTMEG.
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DOI:
10.1155/2011/758973
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发表时间:
2011
影响因子:
--
通讯作者:
Nagarajan SS
Nagarajan SS
中科院分区:
工程技术3区
文献类型:
--
作者:
Dalal SS;Zumer JM;Guggisberg AG;Trumpis M;Wong DD;Sekihara K;Nagarajan SS

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NUTMEG是一个源分析工具箱,面向认知神经科学研究人员使用MEG和EEG,包括颅内记录。可以将激发和未平均的数据导入工具箱,用于时域或时频域的源分析。NUTMEG提供了自适应波束形成器、概率重建算法以及最小范数技术的几种变体,以生成时空神经源活动的功能图。可以从单个和重叠球头模型计算导联场,也可以从其他软件导入。也可以计算组平均值和统计值。除了数据分析工具外,NUTMEG还提供了一个独特直观的图形界面,用于可视化结果。源分析可以叠加到结构MRI或头型上,以提供与解剖结构的方便视觉对应。这些结果也可以交互式导航,空间图和源时间序列或频谱图相应地链接。 可以生成动画来查看神经活动随时间的演变。NUTMEG还可以显示大脑渲染图,并使用SPM的引擎执行功能图的空间标准化。作为一个MATLAB软件包,最终用户可以很容易地与其他工具箱链接或添加自定义功能。
NUTMEG is a source analysis toolbox geared towards cognitive neuroscience researchers using MEG and EEG, including intracranial recordings. Evoked and unaveraged data can be imported to the toolbox for source analysis in either the time or time-frequency domains. NUTMEG offers several variants of adaptive beamformers, probabilistic reconstruction algorithms, as well as minimum-norm techniques to generate functional maps of spatiotemporal neural source activity. Lead fields can be calculated from single and overlapping sphere head models or imported from other software. Group averages and statistics can be calculated as well. In addition to data analysis tools, NUTMEG provides a unique and intuitive graphical interface for visualization of results. Source analyses can be superimposed onto a structural MRI or headshape to provide a convenient visual correspondence to anatomy. These results can also be navigated interactively, with the spatial maps and source time series or spectrogram linked accordingly. Animations can be generated to view the evolution of neural activity over time. NUTMEG can also display brain renderings and perform spatial normalization of functional maps using SPM's engine. As a MATLAB package, the end user may easily link with other toolboxes or add customized functions.
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