Dose-response relationship between protein intake and muscle mass increase: a systematic review and meta-analysis of randomized controlled trials.
Dose-response relationship between protein intake and muscle mass increase: a systematic review and meta-analysis of randomized controlled trials.
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蛋白质摄入与肌肉质量增加之间的剂量反应关系:随机对照试验的系统综述和荟萃分析。
DOI:
10.1093/nutrit/nuaa104
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发表时间:
2020-11-04
影响因子:
6.1
通讯作者:
Miyachi M
中科院分区:
文献类型:
--
作者:
Tagawa R;Watanabe D;Ito K;Ueda K;Nakayama K;Sanbongi C;Miyachi M
Lean body mass is essential for health, yet consensus regarding the effectiveness of protein interventions in increasing lean body mass is lacking. The aim of this systematic review was to evaluate the dose–response relationship of the effects of protein intake on lean body mass. The PubMed and Ichushi-Web databases were searched electronically, and reference lists of the literature included here and in other meta-analyses were searched manually. Randomized controlled trials evaluating the effects of protein intake on lean body mass were included. Two authors independently screened the abstracts; 5 reviewed the full texts. A total of 5402 study participants from 105 articles were included. In the multivariate spline model, the mean increase in lean body mass associated with an increase in protein intake of 0.1 g/kg of body weight per day was 0.39 kg (95%CI, 0.36–0.41) and 0.12 kg (95%CI, 0.11–0.14) below and above the total protein intake of 1.3 g/kg/d, respectively. These findings suggest that slightly increasing current protein intake for several months by 0.1 g/kg/d in a dose-dependent manner over a range of doses from 0.5 to 3.5 g/kg/d may increase or maintain lean body mass. UMIN registration number UMIN000039285.
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影响因子:
3.7
作者:
Moher D;Shamseer L;Clarke M;Ghersi D;Liberati A;Petticrew M;Shekelle P;Stewart LA;PRISMA-P Group
通讯作者:
PRISMA-P Group
影响因子:
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Redman, Leanne M.
影响因子:
7.1
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通讯作者:
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作者:
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通讯作者:
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