Evaluation of Light Physical Activity Measured by Accelerometry and Mobility Disability During a 6-Year Follow-up in Older Women.
Evaluation of Light Physical Activity Measured by Accelerometry and Mobility Disability During a 6-Year Follow-up in Older Women.
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DOI：
10.1001/jamanetworkopen.2021.0005
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发表时间：
2021-02-01
影响因子：
13.8
通讯作者：
Women’s Health Initiative
中科院分区：
文献类型：
--
作者：
Glass NL;Bellettiere J;Jain P;LaMonte MJ;LaCroix AZ;Women’s Health Initiative
在老年妇女中，低强度体力活动与偶发性行动障碍之间是否存在关联？在这项队列研究中，5735名没有活动能力限制的绝经后社区妇女，在6年的随访中，每天平均低强度体力活动的第二、第三和第四四分位数的妇女发生活动能力障碍的风险分别比最低四分位数的妇女低22%、40%和40%。这些结果表明，增加低强度体力活动的建议有可能改善老年妇女保持活动能力的前景。这项队列研究评估了来自美国40个临床站点的数据，以评估老年妇女中轻强度体育活动与意外行动障碍的关系。几乎每四个65岁以上的女性中就有一个无法行走2到3个街区，行动障碍是与丧失独立性相关的一个关键因素。缺乏中等至高强度的身体活动与行动障碍有关，但较轻的身体活动是否与行动障碍有关尚不清楚。确定老年妇女中低强度体力活动与偶发性行动障碍的关系。这项前瞻性队列研究包括2012年3月至2014年4月期间参加客观测量的身体活动和心血管健康研究的女性，这是女性健康倡议的一项辅助研究，随访至2018年3月31日。妇女健康倡议是一项基于人群的多站点研究，从美国40个临床站点招募。本分析的参与者包括7058名63岁及以上的社区流动妇女中的5735名，她们归还了带有可用数据的加速度计，没有行动障碍，并有行动状况的随访数据。数据分析时间为2018年8月至2019年5月。轻强度体力活动，定义为需要1.6至2.9代谢当量的能量消耗的运动，使用加速度计在7天内捕获。事件性行动不便，定义为在年度随访中首次自我报告无法行走1个街区或上一段楼梯，以及持续性事件性行动不便，定义为在随访结束时持续的事件性行动不便。共有5735名参与者被纳入所有事件行动障碍的主要分析（平均[SD]年龄，78.5[6.6]岁[范围，63-97岁]；2811名[49.0%]白人参与者）。与低强度体力活动最低四分位数的女性相比，四分位数2（多变量风险比[HR]， 0.78; 95% CI, 0.67-0.90）、四分位数3 （HR, 0.60; 95% CI, 0.51-0.71）和四分位数4 （HR, 0.60; 95% CI, 0.51-0.71）发生活动障碍的风险较低（P < 0.001）。在四分位数2（多变量HR， 0.72; 95% CI, 0.60-0.85）、四分位数3 （HR, 0.55; 95% CI, 0.46-0.67）和四分位数4 （HR, 0.52; 95% CI, 0.42-0.63）中，这种有益的关联更强（P < 0.001）。分层分析显示，与体重指数为30.0或更高的女性（HR, 0.91; 95% CI; 0.79-1.04; P =）相比，体重指数小于30.0的女性（HR, 0.73; 95% CI, 0.66-0.82）的相关性更强。04表示互动)。在这项队列研究中，增加进行低强度体力活动的时间与减少意外的行动障碍有关。这些发现支持我们更加重视促进低强度的体育活动，以保持晚年的活动能力。
Is there an association between light-intensity physical activity and incident mobility disability among older women? In this cohort study of 5735 postmenopausal, community-dwelling women without mobility limitation, the risk of incident mobility disability over 6 years of follow-up was 22%, 40%, and 40% lower for women in the second, third, and fourth quartiles of daily mean light-intensity physical activity, respectively, compared with the lowest quartile. These results suggest that recommendations to increase light-intensity physical activity have the potential to improve prospects for preserving mobility among older women. This cohort study evaluates data from 40 clinical sites across the US to assess the association of light-intensity physical activity and incident mobility disability among older women. Almost 1 in 4 women older than 65 years is unable to walk 2 to 3 blocks, and mobility disability is a key factor associated with loss of independence. Lack of moderate to vigorous–intensity physical activity is associated with mobility disability, but whether lighter physical activity is associated with mobility disability is unknown. To determine the association of light-intensity physical activity and incident mobility disability among older women. This prospective cohort study included women enrolled in the Objectively Measured Physical Activity and Cardiovascular Health study, an ancillary study of the Women’s Health Initiative, between March 2012 and April 2014, with follow-up through March 31, 2018. The Women’s Health Initiative was a population-based, multisite study that recruited from 40 clinical sites across the US. Participants in the present analysis included 5735 of 7058 ambulatory, community-dwelling women aged 63 years and older who returned an accelerometer with usable data, were free of mobility disability, and had follow-up data on mobility status. Data were analyzed from August 2018 to May 2019. Light-intensity physical activity, defined as movement requiring energy expenditure between 1.6 and 2.9 metabolic equivalents, captured using an accelerometer over 7 days. Incident mobility disability, defined as the first self-reported inability to walk 1 block or up a flight of stairs at annual follow-up, and persistent incident mobility disability, defined as incident mobility loss that persisted through the end of follow-up. A total of 5735 participants were included for primary analysis of all incident mobility disability (mean [SD] age, 78.5 [6.6] years [range, 63-97 years]; 2811 [49.0%] White participants). Compared with women in the lowest quartile of light-intensity physical activity, lower risk of incident mobility disability was observed in quartile 2 (multivariable hazard ratio [HR], 0.78; 95% CI, 0.67-0.90), quartile 3 (HR, 0.60; 95% CI, 0.51-0.71), and quartile 4 (HR, 0.60; 95% CI, 0.51-0.71) (P < .001). This beneficial association was stronger for persistent mobility disability in quartile 2 (multivariable HR, 0.72; 95% CI, 0.60-0.85), quartile 3 (HR, 0.55; 95% CI, 0.46-0.67), and quartile 4 (HR, 0.52; 95% CI, 0.42-0.63) (P < .001). Stratified analyses showed the association was stronger among women with a body mass index of less than 30.0 (HR, 0.73; 95% CI, 0.66-0.82) compared with women with a body mass index of 30.0 or higher (HR, 0.91; 95% CI; 0.79-1.04; P = .04 for interaction). In this cohort study, increased time spent in light-intensity physical activity was associated with reduced incident mobility disability. These findings support placing greater emphasis on promoting light-intensity physical activity for preserving mobility in later life.
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DOI：
10.15585/mmwr.mm6429a2
发表时间：
2015-07-31
期刊：
MMWR. Morbidity and mortality weekly report
影响因子：
--
作者：
Courtney-Long EA;Carroll DD;Zhang QC;Stevens AC;Griffin-Blake S;Armour BS;Campbell VA
通讯作者：
Campbell VA
影响因子：
6.3
作者：
LaMonte MJ;Buchner DM;Rillamas-Sun E;Di C;Evenson KR;Bellettiere J;Lewis CE;Lee IM;Tinker LF;Seguin R;Zaslovsky O;Eaton CB;Stefanick ML;LaCroix AZ
通讯作者：
LaCroix AZ
影响因子：
5.6
作者：
Anderson, GL;Manson, J;Prentice, RL
通讯作者：
Prentice, RL
影响因子：
120.7
作者：
Pahor, Marco;Guralnik, Jack M.;Ambrosius, Walter T.;Blair, Steven;Bonds, Denise E.;Church, Timothy S.;Espeland, Mark A.;Fielding, Roger A.;Gill, Thomas M.;Groessl, Erik J.;King, Abby C.;Kritchevsky, Stephen B.;Manini, Todd M.;McDermott, Mary M.;Miller, Michael E.;Newman, Anne B.;Rejeski, W. Jack;Sink, Kaycee M.;Williamson, Jeff D.
通讯作者：
Williamson, Jeff D.
影响因子：
4.5
作者：
LaCroix AZ;Rillamas-Sun E;Buchner D;Evenson KR;Di C;Lee IM;Marshall S;LaMonte MJ;Hunt J;Tinker LF;Stefanick M;Lewis CE;Bellettiere J;Herring AH
通讯作者：
Herring AH