Accelerometer-Measured Physical Activity and Mortality in Women Aged 63 to 99.
Accelerometer-Measured Physical Activity and Mortality in Women Aged 63 to 99.
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DOI：
10.1111/jgs.15201
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发表时间：
2018-05
影响因子：
6.3
通讯作者：
LaCroix AZ
中科院分区：
文献类型：
--
作者：
LaMonte MJ;Buchner DM;Rillamas-Sun E;Di C;Evenson KR;Bellettiere J;Lewis CE;Lee IM;Tinker LF;Seguin R;Zaslovsky O;Eaton CB;Stefanick ML;LaCroix AZ
前瞻性研究加速计测量的体力活动（PA）和老年妇女死亡率之间的关联，重点是光强度PA。2012年3月至2014年4月期间收集基线数据的前瞻性队列研究。美国妇女健康倡议队列。社区居住妇女，年龄63-99岁（N= 6 382）。通过髋关节佩戴式三轴加速度计测量日常PA的每天分钟数;使用SPPB试验测量身体功能;截至2016年9月的平均3.1年死亡率随访（450例死亡）。当调整加速度计佩戴时间、年龄、种族-民族、教育、吸烟、饮酒、自评健康和合并症时，PA三分位数的全因死亡率（95%置信区间）为1.00（参考），0.86（0.69，1.08），0.80（0.62，1.03）趋势P= 0.07，对于弱光; 1.00，0.57（0.45，0.71），0.47（0.35，0.61）趋势P<.001，对于强光;以及，1.00，0.63（0.50，0.79），0.42（0.30，0.57）趋势P<.001，对于中度至剧烈PA（MVPA）。在进一步调整身体功能后，强光和MVPA的相关性仍然显著（趋势P<0.001）。平均而言，光照（低和高组合）和MVPA每增加30分钟/天与多变量相对风险分别降低12%和39%相关（P<0.01）。在进一步同时调整每个强度后，反向关联仍然显著（光照：0.93（0.89，0.97）; MVPA：0.67（0.58，0.78））。这些相对风险在年龄或人种-种族亚组之间没有差异（相互作用，P≥ .14，所有）。当用加速计测量时，光照强度和MVPA都与老年妇女死亡率的降低有关。这些研究结果表明，用轻PA代替久坐时间是一种公共卫生策略，可以使老龄化社会受益，值得进一步研究。
To prospectively examine associations between accelerometer-measured physical activity (PA) and mortality in older women, with an emphasis on light intensity PA. Prospective cohort study with baseline data collection between March 2012 and April 2014. Women’s Health Initiative cohort in the United States. Community-dwelling women, ages 63–99 (N=6,382). Minutes per day of usual PA measured by hip worn triaxial accelerometers; physical functioning measured using the SPPB test; mortality follow-up for a mean 3.1 years through September 2016 (450 deaths). When adjusted for accelerometer wear time, age, race-ethnicity, education, smoking, alcohol, self-rated health, and comorbidities, relative risks (95% confidence intervals) for all-cause mortality across PA tertiles were 1.00 (referent), 0.86 (0.69, 1.08), 0.80 (0.62, 1.03) trend P=.07, for low light; 1.00, 0.57 (0.45, 0.71), 0.47 (0.35, 0.61) trend P<.001, for high light; and, 1.00, 0.63 (0.50, 0.79), 0.42 (0.30, 0.57) trend P<.001, for moderate-to-vigorous PA (MVPA). Associations remained significant for high light and MVPA (trend P<.001, each) after further adjustment for physical function. Each 30-min/d increment in light (low and high combined) and MVPA was associated, on average, with multivariable relative risk reductions of 12% and 39%, respectively (P<.01, each). After further simultaneous adjustment for each intensity, the inverse associations remained significant (light: 0.93 (0.89, 0.97); MVPA: 0.67 (0.58, 0.78)). These relative risks did not differ between subgroups for age or race-ethnicity (interaction, P≥ .14, all). When measured by accelerometers, both light intensity and MVPA are associated with reduced mortality in older women. These findings suggest replacing sedentary time with light PA is a public health strategy that could benefit an aging society and warrants further investigation.
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影响因子：
2
作者：
DURRLEMAN, S;SIMON, R
通讯作者：
SIMON, R
影响因子：
3.7
作者：
Schmid D;Ricci C;Leitzmann MF
通讯作者：
Leitzmann MF
DOI：
10.1038/oby.2005.165
发表时间：
2005-08-01
期刊：
OBESITY RESEARCH
影响因子：
--
作者：
Plasqui, G;Joosen, AMCP;Westerterp, K
通讯作者：
Westerterp, K
影响因子：
5.6
作者：
Anderson, GL;Manson, J;Prentice, RL
通讯作者：
Prentice, RL
影响因子：
4.5
作者：
LaCroix AZ;Rillamas-Sun E;Buchner D;Evenson KR;Di C;Lee IM;Marshall S;LaMonte MJ;Hunt J;Tinker LF;Stefanick M;Lewis CE;Bellettiere J;Herring AH
通讯作者：
Herring AH