Designing a Strategy Trial for the Management of Gout: The Use of a Modified Delphi Panel.
Designing a Strategy Trial for the Management of Gout: The Use of a Modified Delphi Panel.
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DOI：
10.1002/acr2.11243
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发表时间：
2021-05
影响因子：
3.4
通讯作者：
Barry MJ
中科院分区：
文献类型：
--
作者：
Solomon DH;Weissman JS;Choi H;Atlas SJ;Berardinelli C;Dedier J;Fischer MA;Fitzgerald J;Hinteregger E;Johnsen B;Marini DD;McLean R;Murray F;Neogi T;Oertel LB;Pillinger MH;Riggs KR;Saag K;Suh D;Watkins J;Barry MJ
风湿病学和初级保健协会在痛风管理方面存在分歧。本文描述了一个正式的过程，收集输入的利益相关者在规划的试验比较痛风管理策略。我们招募患者、护士、医师助理、初级保健临床医生和风湿病学家参加改良的德尔菲小组（mDP），为设计一项侧重于初级保健痛风患者最佳管理的试验提供输入。16名小组成员收到了一份简单易懂的简报文件，讨论了试验的基本原理、痛风的关键临床问题以及试验设计的各个方面。小组成员还收到了九个投票问题（VQ）的信息和考虑，被认为是关键的设计问题。与小组成员的认知访谈确保了参与mDP的小组成员范围理解VQ。要求小组成员对所有VQ进行评分，从1（肯定否）到9（肯定是）。投票进行了两轮，第一轮通过电子邮件进行，第二轮通过视频会议进行。通过认知访谈对VQ进行了修正。第一轮投票在8个项目上达成共识，共识定义为相同三分位数（1 - 3，4 - 6或7 - 9）的中位数投票得分。会议再次表决（第二轮）就剩余项目达成共识。与不同利益相关者的mDP促进了对慢性痛风不同管理策略试验设计的共识。这种方法可能是有用的设计临床问题的试验与利益相关者之间的实质性分歧。
Disagreement exists between rheumatology and primary care societies regarding gout management. This paper describes a formal process for gathering input from stakeholders in the planning of a trial to compare gout management strategies. We recruited patients, nurses, physician assistants, primary care clinicians, and rheumatologists to participate in a modified Delphi panel (mDP) to provide input on design of a trial focused on optimal management for primary care patients with gout. The 16 panelists received a plain‐language briefing document that discussed the rationale for the trial, key clinical issues in gout, and aspects of trial design. The panelists also received information and considerations on nine voting questions (VQs), judged to be the key design questions. Cognitive interviews with panelists ensured that the VQs were understood by the range of panelists involved in the mDP. Panelists were asked to score all VQs from 1 (definitely no) to 9 (definitely yes). Two voting rounds were conducted—round 1 by email and round 2 by video conference. The VQs were modified through the cognitive interviews. The round 1 voting resulted in consensus on eight items, with consensus defined as median voting score in the same tercile (1‐3, 4‐6 or 7‐9). Re‐voting at the meeting (round 2) reached consensus on the remaining item. An mDP with various stakeholders facilitated consensus on the design of a trial of different management strategies for chronic gout. This method may be useful for designing trials of clinical questions with substantial disagreement across stakeholders.
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DOI：
10.1002/art.20405
发表时间：
2004-06-15
期刊：
ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH
影响因子：
--
作者：
Shoji, A;Yamanaka, H;Kamatani, N
通讯作者：
Kamatani, N
影响因子：
168.9
作者：
Doherty, Michael;Jenkins, Wendy;Zhang, Weiya
通讯作者：
Zhang, Weiya
影响因子：
3.8
作者：
Drennan, J
通讯作者：
Drennan, J
影响因子：
13.3
作者：
Stamp, Lisa K.;Frampton, Christopher;Richards, A. Mark
通讯作者：
Richards, A. Mark
影响因子：
13.3
作者：
FitzGerald, John D.;Dalbeth, Nicola;Neogi, Tuhina
通讯作者：
Neogi, Tuhina