Echo planar correlated spectroscopic imaging: implementation and pilot evaluation in human calf in vivo.
Echo planar correlated spectroscopic imaging: implementation and pilot evaluation in human calf in vivo.
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DOI：
10.1002/mrm.22499
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发表时间：
2010-10
影响因子：
3.3
通讯作者：
Thomas, M. Albert
中科院分区：
文献类型：
--
作者：
Lipnick, Scott;Verma, Gaurav;Ramadan, Saadallah;Furuyama, Jon;Thomas, M. Albert
关键词：
Exploiting the speed benefits of echo-planar imaging (EPI), the echo-planar spectroscopic imaging (EPSI) sequence facilitates recording of one spectral and two to three spatial dimensions faster than the conventional MR Spectroscopic Imaging (MRSI). A novel four dimensional (4D) echo-planar correlated spectroscopic imaging (EP-COSI) was implemented on a whole body 3T MRI scanner combining two spectral with two spatial encodings. Similar to EPSI, the EP-COSI sequence used a bipolar spatial read-out train facilitating simultaneous spatial and spectral encoding, and the conventional phase and spectral encodings for the other spatial and indirect spectral dimensions, respectively. Multiple 2D correlated spectroscopy (COSY) spectra were recorded over the spatially resolved volume of interest (VOI) localized by a train of three slice-selective radio-frequency (RF) pulses (90°-180°-90°). After the initial optimization using phantom solutions, the EP-COSI data were recorded in the lower leg of eight healthy volunteers including one endurance trained volunteer. Pilot results showed acceptable spatial and spectral quality achievable using the EP-COSI sequence. There was a detectable separation of cross peaks arising from the skeletal muscle intramyocellular lipids (IMCL) and extramyocellular lipids (EMCL) saturated and unsaturated pools. Residual dipolar interaction between the N-methylene and N-methyl protons of creatine/phosphocreatine (Cr/PCr) was also observed in the tibialis anterior region.
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影响因子：
8.2
作者：
Krssak, M;Petersen, KF;Roden, M
通讯作者：
Roden, M
影响因子：
3.3
作者：
Newcomer, Bradley R.;Lawrence, Jeannine C.;den Hollander, Jan A.
通讯作者：
den Hollander, Jan A.
影响因子：
5.8
作者：
Goodpaster, BH;He, J;Kelley, DE
通讯作者：
Kelley, DE
DOI：
10.1152/ajpendo.2002.282.1.e95
发表时间：
2002-01-01
影响因子：
5.1
作者：
Larson-Meyer, DE;Newcomer, BR;Hunter, GR
通讯作者：
Hunter, GR
DOI：
10.1006/jmrb.1996.0163
发表时间：
1996-11-01
期刊：
JOURNAL OF MAGNETIC RESONANCE SERIES B
影响因子：
--
作者：
Kreis, R;Boesch, C
通讯作者：
Boesch, C