Temperature affects the biology of Schmidtea mediterranea.
Temperature affects the biology of Schmidtea mediterranea.
复制标题
DOI:
10.1038/s41598-018-33355-5
复制
发表时间:
2018-10-08
影响因子:
4.6
通讯作者:
Drancourt M
中科院分区:
文献类型:
--
作者:
Hammoudi N;Torre C;Ghigo E;Drancourt M
Studies of tissue regeneration and host-pathogen interactions using the model planarian Schmidtea mediterranea have been performed at an experimental temperature of 19 °C. S. mediterranea planarians exposed to 19 °C–32 °C were observed for survival, mobility, feeding and regeneration for three months and elimination of the Staphylococcus aureus pathogen over six days. S. mediterranea planarians died at 30 °C–32 °C after 18 days of observation but tolerated temperatures of 19 °C up to 28 °C with non-significant differences in mobility and feeding behavior. Genetic malleability tested by RNAi feeding was still efficient at 26 °C and 28 °C. Concerning the immune capacity of planarians, we reported an exacerbation of the immune response in worms infected by S. aureus at 26 °C and 28 °C. These observations suggest a temperature modulation of planarian stem cells and illustrate the importance of modulating experimental temperature when using planarians as model organisms to study regeneration and immune response.
登录
查看更多内容
影响因子:
11.8
作者:
Forsthoefel, David J.;James, Noelle P.;Escobar, David J.;Stary, Joel M.;Vieira, Ana P.;Waters, Forrest A.;Newmark, Phillip A.
通讯作者:
Newmark, Phillip A.
影响因子:
5.2
作者:
Tsoumtsa, Landry Laure;Torre, Cedric;Ghigo, Eric
通讯作者:
Ghigo, Eric
影响因子:
11.8
作者:
Seng, Piseth;Drancourt, Michel;Raoult, Didier
通讯作者:
Raoult, Didier
影响因子:
--
作者:
Child, CM
通讯作者:
Child, CM
DOI:
10.1016/j.cbpb.2009.09.008
发表时间:
2010-01-01
影响因子:
2.2
作者:
An, Myung In;Choi, Cheol Young
通讯作者:
Choi, Cheol Young