Madeiran Arabidopsis thaliana Reveals Ancient Long-Range Colonization and Clarifies Demography in Eurasia.
Madeiran Arabidopsis thaliana Reveals Ancient Long-Range Colonization and Clarifies Demography in Eurasia.
复制标题
DOI：
10.1093/molbev/msx300
复制
发表时间：
2018-03-01
影响因子：
10.7
通讯作者：
Hancock AM
中科院分区：
文献类型：
--
作者：
Fulgione A;Koornneef M;Roux F;Hermisson J;Hancock AM
对岛屿上模式生物的研究可能会揭示罕见的长距离扩散事件，揭示当地进化过程的特征，并为大陆的人口统计推断提供信息。在这里，我们对来自马德拉岛的拟南芥样本的基因组进行了测序。这些样本包括世界上最分歧的，可能是岛上长期隔离的结果。我们推断马德拉岛的殖民化发生在70和85 ka之间，与繁殖体扩散模型（大小≥10）一致，或者与生态机会窗口一致。这代表了一个明显的例子，一个自然的远距离扩散事件在A。thaliana.岛上的长期有效种群规模，而不是创始人效应，对多样性水平和合并率的影响最大。我们的研究结果揭示了欧亚大陆已知易位的祖先单倍型上的选择性扫描签名，以及火山土壤中低磷可用性和海拔高度在塑造早期适应岛屿条件方面的可能重要性。马德拉群岛的基因组避开了大陆人口统计学的复杂性，有助于阐明欧亚大陆的古代人口统计学事件。我们的数据支持一个模型，其中两个独立的谱系A。一个起源于非洲，另一个起源于高加索地区，在伊比利亚扩张并相遇，在那里形成了一个次级接触区。虽然前人的研究认为，A. Thaliana的出现与人类农业的传播相吻合，我们的研究结果表明，它发生在更早的时间（20-40 ka）。
The study of model organisms on islands may shed light on rare long-range dispersal events, uncover signatures of local evolutionary processes, and inform demographic inference on the mainland. Here, we sequenced the genomes of Arabidopsis thaliana samples from the oceanic island of Madeira. These samples include the most diverged worldwide, likely a result of long isolation on the island. We infer that colonization of Madeira happened between 70 and 85 ka, consistent with a propagule dispersal model (of size ≥10), or with an ecological window of opportunity. This represents a clear example of a natural long-range dispersal event in A. thaliana. Long-term effective population size on the island, rather than the founder effect, had the greatest impact on levels of diversity, and rates of coalescence. Our results uncover a selective sweep signature on the ancestral haplotype of a known translocation in Eurasia, as well as the possible importance of the low phosphorous availability in volcanic soils, and altitude, in shaping early adaptations to the island conditions. Madeiran genomes, sheltered from the complexities of continental demography, help illuminate ancient demographic events in Eurasia. Our data support a model in which two separate lineages of A. thaliana, one originating in Africa and the other from the Caucasus expanded and met in Iberia, resulting in a secondary contact zone there. Although previous studies inferred that the westward expansion of A. thaliana coincided with the spread of human agriculture, our results suggest that it happened much earlier (20–40 ka).
登录
查看更多内容
影响因子：
4.5
作者：
Gutenkunst RN;Hernandez RD;Williamson SH;Bustamante CD
通讯作者：
Bustamante CD
影响因子：
4.3
作者：
Kelleher J;Etheridge AM;McVean G
通讯作者：
McVean G
影响因子：
1.2
作者：
Cingolani, Pablo;Platts, Adrian;Ruden, Douglas M.
通讯作者：
Ruden, Douglas M.
影响因子：
7.2
作者：
Alonso-Blanco, C;Peeters, AJM;Kuiper, MTR
通讯作者：
Kuiper, MTR
影响因子：
30.8
作者：
Long, Quan;Rabanal, Fernando A.;Meng, Dazhe;Huber, Christian D.;Farlow, Ashley;Platzer, Alexander;Zhang, Qingrun;Vilhjalmsson, Bjarni J.;Korte, Arthur;Nizhynska, Viktoria;Voronin, Viktor;Korte, Pamela;Sedman, Laura;Mandakova, Terezie;Lysak, Martin A.;Seren, Uemit;Hellmann, Ines;Nordborg, Magnus
通讯作者：
Nordborg, Magnus