Genome-wide prediction of transcription factor binding sites using an integrated model.
Genome-wide prediction of transcription factor binding sites using an integrated model.
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DOI：
10.1186/gb-2010-11-1-r7
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发表时间：
2010-01-22
期刊：
影响因子：
12.3
通讯作者：
Wang W
中科院分区：
文献类型：
--
作者：
Won KJ;Ren B;Wang W
A new approach for genome-wide transcription factor binding site prediction is presented that integrates sequence and chromatin modification data. We present an integrated method called Chromia for the genome-wide identification of functional target loci of transcription factors. Designed to capture the characteristic patterns of transcription factor binding motif occurrences and the histone profiles associated with regulatory elements such as promoters and enhancers, Chromia significantly outperforms other methods in the identification of 13 transcription factor binding sites in mouse embryonic stem cells, evaluated by both binding (ChIP-seq) and functional (RNA interference knockdown) experiments.
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影响因子：
64.8
作者：
Heintzman, Nathaniel D.;Hon, Gary C.;Hawkins, R. David;Kheradpour, Pouya;Stark, Alexander;Harp, Lindsey F.;Ye, Zhen;Lee, Leonard K.;Stuart, Rhona K.;Ching, Christina W.;Ching, Keith A.;Antosiewicz-Bourget, Jessica E.;Liu, Hui;Zhang, Xinmin;Green, Roland D.;Lobanenkov, Victor V.;Stewart, Ron;Thomson, James A.;Crawford, Gregory E.;Kellis, Manolis;Ren, Bing
通讯作者：
Ren, Bing
影响因子：
64.5
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Orkin, Stuart H.
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Kim, Tae Hoon;Abdullaev, Ziedulla K.;Ren, Bing
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Ren, Bing
TransFac及其模块移植：真核生物中的转录基因调节。
影响因子：
14.9
作者：
Matys V;Kel-Margoulis OV;Fricke E;Liebich I;Land S;Barre-Dirrie A;Reuter I;Chekmenev D;Krull M;Hornischer K;Voss N;Stegmaier P;Lewicki-Potapov B;Saxel H;Kel AE;Wingender E
通讯作者：
Wingender E
影响因子：
14.9
作者：
Frith, MC;Li, MC;Weng, ZP
通讯作者：
Weng, ZP