Lactational programming? Mother's milk energy predicts infant behavior and temperament in rhesus macaques (Macaca mulatta).
Lactational programming? Mother's milk energy predicts infant behavior and temperament in rhesus macaques (Macaca mulatta).
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DOI：
10.1002/ajp.20806
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发表时间：
2010-06
影响因子：
2.4
通讯作者：
Captanio, John P.
中科院分区：
文献类型：
--
作者：
Hinde, Katie;Captanio, John P.
有许多方面的“母亲”，可以提供信息，哺乳动物婴儿的环境条件，在关键时期的发展。母性的一个基本要素涉及母亲为婴儿提供的乳汁的数量和质量，但对乳汁产量变化的后果知之甚少。母乳可以通过促进大脑发育和行为倾向的发展来影响婴儿的行为。在这里，我们提出的第一个证据，任何哺乳动物的自然变化，在可用的牛奶能量（AME）从母亲是与后来的变化，在婴儿的行为和气质的恒河猴（猕猴，N=59）。在产后早期，体重较重的母亲，更多的生殖经验产生更大的AME，这是牛奶能量密度（千卡/克）和牛奶产量（克）的产品。此外，母亲在出生后早期产生更大AME的婴儿在婴儿期后期的压力环境中表现出更高的活动水平和更大的信心。我们的研究结果表明，出生后不久可获得的牛奶能量可能是一种营养提示，可以根据环境或母体条件调整婴儿的行为。这些数据为行为和气质发展的潜在机制提供了新的见解，并为研究母体效应、营养规划和发育可塑性指明了新的方向。
There are many of aspects of “mothering” that may provide information to the mammalian infant about environmental conditions during critical periods of development. One essential element of mothering involves the quantity and quality of milk that mothers provide for their infants, but little is known about the consequences of variation in milk production. Mother’s milk may affect infant behavior by contributing to brain development and to the development of behavioral dispositions. Here we present the first evidence for any mammal that natural variation in available milk energy (AME) from the mother is associated with later variation in infant behavior and temperament in rhesus macaques (Macaca mulatta, N=59). In the early post-natal period, heavier mothers with more reproductive experience produced greater AME, which is the product of milk energy density (kcal/g) and milk yield (g). Moreover, infants whose mothers produced greater AME in the early post-natal period showed higher activity levels and greater confidence in a stressful setting later in infancy. Our results suggest that the milk energy available soon after birth may be a nutritional cue that calibrates the infant’s behavior to environmental or maternal conditions. These data provide new insight into potential mechanisms for the development of behavior and temperament and illuminate new directions for investigating maternal effects, nutritional programming, and developmental plasticity.
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影响因子：
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作者：
Kuzawa, Christopher W.
通讯作者：
Kuzawa, Christopher W.
影响因子：
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作者：
Barker, DJP;Eriksson, JG;Osmond, C
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JACOBS, B;CHUGANI, HT;RALEIGH, MJ
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