Profiles of primary aromatic amines, nicotine, and cotinine in indoor dust and associated human exposure in China.
Profiles of primary aromatic amines, nicotine, and cotinine in indoor dust and associated human exposure in China.
复制标题
DOI：
10.1016/j.scitotenv.2021.151395
复制
发表时间：
2022-02-01
期刊：
影响因子：
--
通讯作者：
Kannan K
中科院分区：
文献类型：
--
作者：
Chinthakindi S;Zhu Q;Liao C;Kannan K
尽管芳香伯胺（AA）在消费品中的广泛使用，但对其在室内灰尘中的流行情况知之甚少。在这项研究中，我们调查了35个AA和两个烟草化学标记物（尼古丁和其分解产物可替宁）在119个样品中收集的中国五个省的家尘。35种AA中的10种和[尼古丁和/或可替宁]分别在> 80%和100%的样本中发现，浓度范围分别为29.1 - 19，200（中位数：700 ng/g）和23.2 - 22，400（4，600）ng/g。苯胺是所有灰尘样本中发现的主要AA（中位数：257纳克/克）。河南和山西两省的粉尘样品中10种AA的总浓度高于四川和山东两省，但五省之间的差异不显著（p> 0.05）。一个显着的（p = 0.048），正相关（r = 0.882）之间存在的尼古丁和可替宁的粉尘样品中的浓度。同样，AA的浓度显着相关，与灰尘样品中的尼古丁。染料、橡胶制品、聚氨酯泡沫塑料和烟草烟雾是室内环境中AA的主要来源。通过粉尘摄入的估计每日摄入量（EDI）范围为0.349（成人）至6.62纳克/千克-bw/天（幼儿）的AA和1.27至51.1纳克/千克-bw/天的尼古丁，低于目前的每日可耐受摄入量。
Despite the widespread use of primary aromatic amines (AAs) in consumer products, little is known about their prevalence in house dust. In this study, we investigated the occurrence of 35 AAs and two tobacco chemical markers (nicotine and its breakdown product cotinine) in 119 samples of house dust collected from five provinces in China. Ten of the 35 AAs and [nicotine and/or cotinine] were found in >80% and 100% of the samples, respectively, at concentration ranges of 29.1–19,200 (median: 700 ng/g) and 23.2–22,400 (4,600) ng/g, respectively. Aniline was the predominant AA found in all dust samples (median: 257 ng/g). Dust samples from Henan and Shanxi provinces contained higher summed concentrations of the 10 AAs than those from Sichuan and Shandong, although the concentrations did not vary significantly among the five provinces (p > 0.05). A significant (p = 0.048), positive correlation (r = 0.882) existed between concentrations of nicotine and cotinine in dust samples. Similarly, concentrations of AAs were significantly correlated with those of nicotine in dust samples. Dyestuffs, rubber products, polyurethane foam and tobacco smoke are the major sources of AAs in the indoor environment. The estimated daily intakes (EDI) through dust ingestion ranged from 0.349 (adults) to 6.62 ng/kg-bw/day (toddlers) for AAs and from 1.27 to 51.1 ng/kg-bw/day for nicotine which are below the current tolerable daily intakes.
登录
查看更多内容
DOI：
10.1080/15459624.2012.693836
发表时间：
2012-01-01
影响因子：
2
作者：
Hanley, Kevin W.;Viet, Susan M.;Ruder, Avima M.
通讯作者：
Ruder, Avima M.
影响因子：
11.4
作者：
Mitro, Susanna D.;Dodson, Robin E.;Singla, Veena;Adarnkiewicz, Gary;Elmi, Angelo F.;Tilly, Monica K.;Zota, Ami R.
通讯作者：
Zota, Ami R.
DOI：
10.1016/j.jchromb.2021.122888
发表时间：
2021-08-15
期刊：
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
影响因子：
--
作者：
Chinthakindi S;Kannan K
通讯作者：
Kannan K
影响因子：
6.2
作者：
Marand, A;Karlsson, D;Skarping, G
通讯作者：
Skarping, G
DOI：
10.1080/19440049.2013.867366
发表时间：
2014-03-04
影响因子：
2.9
作者：
Paseiro-Cerrato, R.;Noonan, G. O.;Begley, T. H.
通讯作者：
Begley, T. H.