Prevalence and Correlates of Hepatitis C Virus Infection among Street-Recruited Injection Drug Users in San Juan, Puerto Rico
Prevalence and Correlates of Hepatitis C Virus Infection among Street-Recruited Injection Drug Users in San Juan, Puerto Rico
复制标题
波多黎各圣胡安街头招募的注射吸毒者丙型肝炎病毒感染的患病率和相关性
DOI：
--
复制
发表时间：
2006
期刊：
影响因子：
--
通讯作者：
Elizabeth Shepard
中科院分区：
文献类型：
--
作者：
J. Reyes;H. Colón;R. Robles;E. Ríos;T. Matos;J. Negrón;C. Marrero;J. Calderón;Elizabeth Shepard
在世界各地，注射吸毒者 (IDU) 是丙型肝炎病毒 (HCV) 感染风险最高的群体。居住在波多黎各岛的注射吸毒者和居住在美国大陆的波多黎各注射吸毒者已被证明感染艾滋病毒的风险非常高。然而，HCV 感染在波多黎各注射吸毒者中传播的程度尚不清楚。本研究的目的是估计 HCV 血清流行率并确定与 HCV 传播相关的相关性。该样本是通过街头外展策略抽取的，由居住在圣胡安大都市区的 400 名未接受治疗的注射吸毒者组成。采用酶联免疫吸附法检测HCV和HIV感染，并通过Western blot验证结果。有关社会人口统计、吸毒模式和危险行为的信息是通过结构化访谈获得的。使用双变量分析和多变量逻辑回归来评估 HCV 感染的协变量。 HCV感染率为89%。在控制了社会人口统计学特征后，HCV 感染与注射年限、在射击场注射、在监狱纹身以及自我报告的 STD 感染呈正相关。值得注意的是，在研究访谈前一年内开始注射毒品的注射吸毒者的 HCV 感染率为 57%。这项研究表明，波多黎各迫切需要采取更积极的教育计划来减少 HCV 感染在注射吸毒者中的传播。
Throughout the world, injection drug users (IDUs) are the group at highest risk for hepatitis C virus (HCV) infection. IDUs residing in the island of Puerto Rico and Puerto Rican IDUs residing in the U.S. mainland have been shown to be at very high risk of infection with HIV. However, the extent to which HCV infection has spread among IDUs in Puerto Rico is not yet known. The aims of this study were to estimate seroprevalence of HCV and to identify the correlates associated with HCV transmission. The sample was drawn through street outreach strategies and was comprised of 400 injection drug users not in treatment, living in the San Juan metropolitan area. HCV and HIV infection were detected by enzyme-linked immunosorbent assay and the results were confirmed by Western blot. Information on sociodemographics, drug use patterns, and risk behaviors was obtained through structured interviews. Bivariate analyses and multivariate logistic regression were used to assess covariates of infection with HCV. The prevalence of HCV infection was 89%. After controlling for sociodemographic characteristics, HCV infection was positively associated with increasing years of injection, injecting in a shooting gallery, tattooing in prison, and self-reported STD infection. Notably, IDUs who had initiated drug injection within the year prior to the study interview had an HCV infection rate of 57%. This study indicates that more aggressive educational programs are urgently needed to reduce the spread of HCV infection among IDUs in Puerto Rico.
登录
查看更多内容
波多黎各静脉吸毒者的行为危险因素和人类免疫缺陷病毒（HIV）患病率。
影响因子：
5
作者：
Robles,RR;Colón,HM;Sahai,H;Matos,TD;Marrero,CA;Reyes,JC
通讯作者：
Reyes,JC
影响因子：
12.7
作者：
Garfein, RS;Vlahov, D;Nelson, KE
通讯作者：
Nelson, KE
影响因子：
7.7
作者：
Garten, RJ;Lai, SH;Yu, XF
通讯作者：
Yu, XF
波多黎各注射吸毒者的无家可归和艾滋病毒危险行为。
DOI：
10.1093/jurban/jti073
发表时间：
2005
期刊：
Journal of urban health : bulletin of the New York Academy of Medicine.
影响因子：
--
作者：
Reyes,JuanC;Robles,RafaelaR;Colon,HectorM;Matos,TomasD;Finlinson,HAnn;Marrero,CAmalia;Shepard,ElizabethW
通讯作者：
Shepard,ElizabethW
全国吸毒者样本中西班牙裔人群的艾滋病毒风险估计。
DOI：
10.1097/00126334-199905010-00006
发表时间：
1999
期刊：
Journal of acquired immune deficiency syndromes (1999)
影响因子：
--
作者：
Montoya,ID;Bell,DC;Richard,AJ;Carlson,JW;Trevino,RA
通讯作者：
Trevino,RA