3D reconstructions of quail-chick chimeras provide a new fate map of the avian scapula.
3D reconstructions of quail-chick chimeras provide a new fate map of the avian scapula.
复制标题
鹌鹑雏鸡嵌合体的 3D 重建提供了鸟类肩胛骨的新命运图。
DOI:
10.1016/j.ydbio.2011.03.032
复制
发表时间:
2011
影响因子:
2.7
通讯作者:
Burke,AnnC
中科院分区:
文献类型:
--
作者:
Shearman,RebeccaM;Tulenko,FrankJ;Burke,AnnC
Limbed vertebrates have functionally integrated postcranial axial and appendicular systems derived from two distinct populations of embryonic mesoderm. The axial skeletal elements arise from the paraxial somites, the appendicular skeleton and sternum arise from the somatic lateral plate mesoderm, and all of the muscles for both systems arise from the somites. Recent studies in amniotes demonstrate that the scapula has a mixed mesodermal origin. Here we determine the relative contribution of somitic and lateral plate mesoderm to the avian scapula from quail-chick chimeras. We generate 3D reconstructions of the grafted tissue in the host revealing a very different distribution of somitic cells in the scapula than previously reported. This novel 3D visualization of the cryptic border between somitic and lateral plate populations reveals the dynamics of musculoskeletal morphogenesis and demonstrates the importance of 3D visualization of chimera data. Reconstructions of chimeras make clear three significant contrasts with existing models of scapular development. First, the majority of the avian scapula is lateral plate derived and the somitic contribution to the scapular blade is significantly smaller than in previous models. Second, the segmentation of the somitic component of the blade is partially lost; and third, there are striking differences in growth rates between different tissues derived from the same somites that contribute to the structures of the cervical thoracic transition, including the scapula. These data call for the reassessment of theories on the development, homology, and evolution of the vertebrate scapula.
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DOI:
--
发表时间:
1977
期刊:
Anatomy and Embryology
影响因子:
--
作者:
B. Christ;H. J. Jacob;M. Jacob
通讯作者:
M. Jacob
影响因子:
4.6
作者:
A. Burke;Craig E. Nelson;B. Morgan
通讯作者:
A. Burke;Craig E. Nelson;B. Morgan
影响因子:
--
作者:
Burke,AC
通讯作者:
Burke,AC
DOI:
10.1007/s00429-004-0415-0
发表时间:
2004
期刊:
Anatomy and Embryology
影响因子:
--
作者:
F. Ehehalt;Baigang Wang;B. Christ;K. Patel;Ruijin Huang
通讯作者:
Ruijin Huang
DOI:
10.1002/jez.b.21246
发表时间:
2009
期刊:
Journal of experimental zoology. Part B, Molecular and developmental evolution
影响因子:
--
作者:
Shearman,RebeccaMarie;Burke,AnnCampbell
通讯作者:
Burke,AnnCampbell