Integrated Stent Models Based on Dimension Reduction: Review and Future Perspectives
Integrated Stent Models Based on Dimension Reduction: Review and Future Perspectives
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基于降维的集成支架模型：回顾与未来展望
DOI：
--
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发表时间：
2016
影响因子：
3.8
通讯作者：
F. Migliavacca
中科院分区：
文献类型：
--
作者：
P. Zunino;J. Tambača;Elena Cutri;S. Čanić;L. Formaggia;F. Migliavacca
由于支架的多物理性质和这些器械的复杂几何结构，支架建模从理论和数值角度来看都是一项具有挑战性的任务。在这种情况下，降维模型能够以负担得起的计算成本对支架植入术进行全面的几何和物理描述。在这项工作中，我们的目的是审查降维模型的支架力学和药物释放。首先，我们解决模型简化技术的支架力学的描述，旨在说明如何三维支架模型可以转换成一个集合的互连的一维杆，称为“支架网”。其次，我们回顾了现有的模型降阶方法同样适用于药物释放，其中“支架网”的概念是通过建模的药物洗脱。因此，药物洗脱支架被描述为位于完全代表支架几何形状的图上的集中药物释放源的分布。最后，还讨论了将这些模型简化方法扩展到生物可降解支架的新结果。
Stent modeling represents a challenging task from both the theoretical and numerical viewpoints, due to its multi-physics nature and to the complex geometrical configuration of these devices. In this light, dimensional model reduction enables a comprehensive geometrical and physical description of stenting at affordable computational costs. In this work, we aim at reviewing dimensional model reduction of stent mechanics and drug release. Firstly, we address model reduction techniques for the description of stent mechanics, aiming to illustrate how a three-dimensional stent model can be transformed into a collection of interconnected one-dimensional rods, called a “stent net”. Secondly, we review available model reduction methods similarly applied to drug release, in which the “stent net” concept is adopted for modeling of drug elution. As a result, drug eluting stents are described as a distribution of concentrated drug release sources located on a graph that fully represents the stent geometry. Lastly, new results about the extension of these model reduction approaches to biodegradable stents are also discussed.
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影响因子：
3.3
作者：
Caiazzo, Alfonso;Evans, David;Hoekstra, Alfons
通讯作者：
Hoekstra, Alfons
影响因子：
2.4
作者：
Menzel A;Kuhl E
通讯作者：
Kuhl E
DOI：
10.1016/j.jconrel.2012.05.039
发表时间：
2012-08-10
期刊：
Journal of controlled release : official journal of the Controlled Release Society
影响因子：
--
作者：
Tzafriri AR;Groothuis A;Price GS;Edelman ER
通讯作者：
Edelman ER
影响因子：
10.8
作者：
Balakrishnan, Brinda;Dooley, John F.;Edelman, Elazer R.
通讯作者：
Edelman, Elazer R.