Integrating structural and epidemiological research to inform the classification of psychopathology.

Integrating structural and epidemiological research to inform the classification of psychopathology.
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DOI:
10.1002/mpr.295
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发表时间:
2009-12
影响因子:
3.1
通讯作者:
Ruscio, Ayelet Meron
Ruscio, Ayelet Meron
中科院分区:
医学3区
文献类型:
--
作者:
Ruscio, Ayelet Meron

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鉴于分类对精神卫生专业人员的主要临床、研究和行政活动的巨大影响,了解疾病的真实数量和性质及其合并症的原因是一个重要的公共卫生优先事项。然而,虽然潜在结构的研究已经产生了有价值的信息障碍的边界,他们依赖于非代表性的样本和未能评估的实际意义的结构研究结果限制了他们的能力,影响疾病分类学的变化。相反,社区流行病学研究通过评估代表性样本中诊断标准的影响来为分类提供信息,但由于其重点是精神障碍,因此受到限制,因为目前精神障碍是由该领域概念化的,而不是这些疾病实际存在于自然界中的相关因素和后果。我认为系统地整合结构研究方法与流行病学研究方法的潜在价值,探索五种方式,这些基本上独立的传统可以有益地结合起来,为精神障碍的下一个分类提供信息。通过利用结构和流行病学研究的互补优势,综合方法具有显著的潜力,以促进对精神病理学性质的理解,并提高其诊断的有效性和实用性。
Given the enormous influence of classification on the major clinical, research, and administrative activities of mental health professionals, understanding the true number and nature of disorders and the reasons for their comorbidity is an important public health priority. However, while studies of latent structure have yielded valuable information about disorder boundaries, their reliance on nonrepresentative samples and failure to evaluate the practical implications of structural findings has limited their ability to effect nosological change. Conversely, community epidemiology studies, which inform classification by assessing the implications of diagnostic criteria in representative samples, have been limited by their focus on mental disorders as they are currently conceptualized by the field rather than on correlates and consequences of these disorders as they actually exist in nature. I consider the potential value of integrating systematically the methods of structural research with the methods of epidemiological research, exploring five ways in which these largely independent traditions may profitably be combined to inform the next classifications of mental disorders. By capitalizing on the complementary strengths of structural and epidemiological research, an integrated approach has significant potential to advance understanding of the nature of psychopathology and improve the validity and utility of its diagnosis.
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