The effect of unilateral superior laryngeal nerve lesion on swallowing threshold volume.
The effect of unilateral superior laryngeal nerve lesion on swallowing threshold volume.
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DOI：
10.1002/lary.24051
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发表时间：
2013-08
期刊：
影响因子：
2.6
通讯作者：
German, Rebecca Z.
中科院分区：
文献类型：
--
作者：
Ding, Peng;Campbell-Malone, Regina;Holman, Shaina D.;Lukasik, Stacey L.;Thexton, Allan J.;German, Rebecca Z.
关键词：
上级喉神经（SLN）是上喉的主要感觉神经。该神经的损伤会影响吞咽的成功。本研究的第一个目的是评估单侧SLN病变对完整猪模型中足以引起吞咽的阈值体积的影响;该体积在放射学上定义为侧视图中可见的最大团注面积。第二个目的是确定单侧感觉丧失导致的同侧和对侧功能之间是否存在差异，测量为谷中所见液体的放射学密度。最后，我们确定了单侧SLN病变后阈值体积和误吸发生率之间是否存在关系。重复测量动物研究。四只雌性幼猪接受单侧SLN病变手术。在损伤前对照和损伤后实验状态下，从视频荧光镜记录中获得侧视图中的最大谷团面积和背腹侧视图中每侧的相对谷密度。在侧位片上，病变组的最大团注面积大于对照组（P<0.001）。尽管在背腹侧视图中偶尔观察到左右不对称，但平均而言，左侧（完整）和右侧（病变）的谷密度相等（p>0.05）。病灶组中，较大的最大团注面积并不能预测误吸（p>0.05）。单侧SLN病变可对称性地增加左右两侧谷的吞咽阈值容量，但阈值增加可能不是误吸发生的主要机制。单侧SLN毁损对吞咽阈值容量的影响
The Superior Laryngeal Nerve (SLN) is the major sensory nerve for the upper larynx. Damage to this nerve impacts on successful swallowing. The first aim of the study was to assess the effect of unilateral SLN lesion on the threshold volume sufficient to elicit swallowing in an intact pig model; this volume was defined radiographically as the maximum bolus area visible in lateral view. The second aim was to determine if a difference existed between ipsi-lateral and contra-lateral function as a result of unilateral sensory loss, measured as the radiologic density of fluid seen in the valleculae. Finally, we determined if there was a relationship between the threshold volume and the occurrence of aspiration after a unilateral SLN lesion. Repeated measures animal study. Four female infant pigs underwent unilateral SLN lesion surgery. The maximum vallecular bolus area in lateral view and the relative vallecular density on each side in the dorsoventral view were obtained from videofluoroscopic recordings in both the pre-lesion control and post lesion experimental states. In lateral view, the lesioned group had a bigger maximum bolus area than the control group (p<0.001). Although occasional left-right asymmetry in the dorsoventral view was observed,, the vallecular densities were, on average, equal on both the left (intact) and right (lesioned) sides (p>0.05). A bigger maximum bolus area did not predict aspiration in the lesioned group (p>0.05). Unilateral SLN lesions increased the swallowing threshold volume symmetrically in right and left valleculae but the increased threshold may not be the main mechanism for the occurrence of aspiration. The Effect of Unilateral SLN Lesion on Swallowing Threshold Volume
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影响因子：
3.5
作者：
Shaker, R;Ren, JL;Kern, M
通讯作者：
Kern, M
影响因子：
2.5
作者：
German, Rebecca Z.;Crompton, A. W.;Thexton, Allan J.
通讯作者：
Thexton, Allan J.
影响因子：
2.9
作者：
Fontijn-Tekamp, FA;van der Bilt, A;Bosman, F
通讯作者：
Bosman, F
DOI：
10.1152/ajpgi.1998.275.3.g521
发表时间：
1998-09-01
影响因子：
4.5
作者：
Shaker, R;Medda, BK;Lang, IM
通讯作者：
Lang, IM
影响因子：
2.6
作者：
Aviv, JE;Sacco, RL;Close, LG
通讯作者：
Close, LG