Magnetic particle imaging for radiation-free, sensitive and high-contrast vascular imaging and cell tracking.
Magnetic particle imaging for radiation-free, sensitive and high-contrast vascular imaging and cell tracking.
复制标题
无辐射,灵敏和高对比度血管成像和细胞跟踪的磁性粒子成像。
DOI:
10.1016/j.cbpa.2018.04.014
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发表时间:
2018-08
影响因子:
7.8
通讯作者:
Conolly SM
中科院分区:
文献类型:
--
作者:
Zhou XY;Tay ZW;Chandrasekharan P;Yu EY;Hensley DW;Orendorff R;Jeffris KE;Mai D;Zheng B;Goodwill PW;Conolly SM
Magnetic particle imaging (MPI) is an emerging ionizing radiation-free biomedical tracer imaging technique that directly images the intense magnetization of superparamagnetic iron oxide nanoparticles (SPIOs). MPI offers ideal image contrast because MPI shows zero signal from background tissues. Moreover, there is zero attenuation of the signal with depth in tissue, allowing for imaging deep inside the body quantitatively at any location. Recent work has demonstrated the potential of MPI for robust, sensitive vascular imaging and cell tracking with high contrast and dose-limited sensitivity comparable to nuclear medicine. To foster future applications in MPI, this new biomedical imaging field is welcoming researchers with expertise in imaging physics, magnetic nanoparticle synthesis and functionalization, nanoscale physics, and small animal imaging applications.
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