Cardiac Shockwave Therapy - A Novel Therapy for Ischemic Cardiomyopathy?
Cardiac Shockwave Therapy - A Novel Therapy for Ischemic Cardiomyopathy?
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DOI:
10.3389/fcvm.2022.875965
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发表时间:
2022
影响因子:
3.6
通讯作者:
中科院分区:
文献类型:
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作者:
Over the past decades, shockwave therapy (SWT) has gained increasing interest as a therapeutic approach for regenerative medicine applications, such as healing of bone fractures and wounds. More recently, pre-clinical studies have elucidated potential mechanisms for the regenerative effects of SWT in myocardial ischemia. The mechanical stimulus of SWT may induce regenerative effects in ischemic tissue via growth factor release, modulation of inflammatory response, and angiogenesis. Activation of the innate immune system and stimulation of purinergic receptors by SWT appears to enhance vascularization and regeneration of injured tissue with functional improvement. Intriguingly, small single center studies suggest that SWT may improve angina, exercise tolerance, and hemodynamics in patients with ischemic heart disease. Thus, SWT may represent a promising technology to induce cardiac protection or repair in patients with ischemic heart disease.
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影响因子:
1.9
作者:
Burneikaitė G;Shkolnik E;Čelutkienė J;Zuozienė G;Butkuvienė I;Petrauskienė B;Šerpytis P;Laucevičius A;Lerman A
通讯作者:
Lerman A
影响因子:
--
作者:
Cooke JP;Connor JH;Jain A
通讯作者:
Jain A
影响因子:
20.1
作者:
Abdellatif, Mahmoud;Sedej, Simon;Kroemer, Guido
通讯作者:
Kroemer, Guido
影响因子:
3.7
作者:
Berta, Laura;Fazzari, Annamaria;Frairia, Roberto
通讯作者:
Frairia, Roberto
影响因子:
20.1
作者:
Aicher, Alexandra;Rentsch, Markus;Heeschen, Christopher
通讯作者:
Heeschen, Christopher