Mosquito immune defenses against Plasmodium infection.
Mosquito immune defenses against Plasmodium infection.
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DOI:
10.1016/j.dci.2009.12.005
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发表时间:
2010-04
影响因子:
2.9
通讯作者:
Dimopoulos, George
中科院分区:
文献类型:
--
作者:
Cirimotich, Chris M.;Dong, Yuemei;Garver, Lindsey S.;Sim, Shuzhen;Dimopoulos, George
The causative agent of malaria, Plasmodium, has to undergo complex developmental transitions and survive attacks from the mosquito's innate immune system to achieve transmission from one host to another through the vector. Here we discuss recent findings on the role of the mosquito's innate immune signaling pathways in preventing infection by the Plasmodium parasite, the identification and mechanistic description of novel anti-parasite molecules, the role that natural bacteria harbored in the mosquito midgut might play in this immune defense, and the crucial parasite and vector molecules that mediate midgut infection.
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影响因子:
9.8
作者:
Dong, Yuemei;Taylor, Harry E;Dimopoulos, George
通讯作者:
Dimopoulos, George
影响因子:
6.7
作者:
Dong Y;Aguilar R;Xi Z;Warr E;Mongin E;Dimopoulos G
通讯作者:
Dimopoulos G
影响因子:
6.7
作者:
Baker RP;Wijetilaka R;Urban S
通讯作者:
Urban S
DOI:
10.1073/pnas.0404952102
发表时间:
2005-01-25
影响因子:
11.1
作者:
Choe, KM;Lee, H;Anderson, KV
通讯作者:
Anderson, KV
影响因子:
2.9
作者:
Arrighi, Romanico B. G.;Debierre-Grockiege, Francoise;Faye, Ingrid
通讯作者:
Faye, Ingrid