Primary relationships, HIV treatment adherence, and virologic control.

Primary relationships, HIV treatment adherence, and virologic control.
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DOI:
10.1007/s10461-011-0021-0
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发表时间:
2012-08
期刊:
影响因子:
4.4
通讯作者:
Neilands, Torsten B.
Neilands, Torsten B.
中科院分区:
医学2区
文献类型:
--
作者:
Johnson, Mallory O.;Dilworth, Samantha E.;Taylor, Jonelle M.;Darbes, Lynae A.;Comfort, Megan L.;Neilands, Torsten B.

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为了确定与抗逆转录病毒治疗(ART)的依从性和艾滋病毒阳性的男性ART的主要关系中的病毒控制的相关因素,数据收集了210名男性夫妇(420名男性)。二元行为者-合作者分析研究了与三个水平的依从性相关的因变量:自我效能(ASE),自我报告的依从性和病毒学控制。结果表明,较高的患者ASE与他自己对药物的积极信念,较高的关系自主性和亲密度,以及较少的抑郁症状有关。伴侣中抑郁症状较少和关系满意度较低与患者的ASE较高有关。更好的自我报告的依从性与患者的积极评价的关系和合作伙伴的积极治疗效果的信念。患者和伴侣对药物的担忧越大,依从性越低。伴侣的较高关系承诺与患者的较低病毒载量相关。研究结果表明,抑郁症状,治疗信念,双方的合作伙伴的关系质量因素可能会影响依从性相关的结果。
To identify factors associated with antiretroviral therapy (ART) adherence and virologic control among HIV-positive men on ART in primary relationships, data were collected from 210 male couples (420 men). Dyadic actor–partner analyses investigated associations with three levels of adherence-related dependent variables: self-efficacy (ASE), self-reported adherence, and virologic control. Results indicated that higher patient ASE was related to his own positive beliefs about medications, higher relationship autonomy and intimacy, and fewer depressive symptoms. Fewer depressive symptoms and less relationship satisfaction in the partner were linked to higher ASE in the patient. Better self-reported adherence was related to the patient’s positive appraisal of the relationship and the partner’s positive treatment efficacy beliefs. Greater medication concerns of both patient and partner were associated with less adherence. The partner’s higher relationship commitment was associated with lower viral load in the patient. Findings suggest that depressive symptoms, treatment beliefs, and relationship quality factors of both partners may influence adherence-related outcomes.
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