Normal limits in relation to age, body size and gender of two-dimensional echocardiographic aortic root dimensions in persons ≥15 years of age.
Normal limits in relation to age, body size and gender of two-dimensional echocardiographic aortic root dimensions in persons ≥15 years of age.
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DOI：
10.1016/j.amjcard.2012.05.063
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发表时间：
2012-10-15
影响因子：
2.8
通讯作者：
Roman, Mary J.
中科院分区：
文献类型：
--
作者：
Devereux, Richard B.;de Simone, Giovanni;Arnett, Donna K.;Best, Lyle G.;Boerwinkle, Eric;Howard, Barbara V.;Kitzman, Lane;Lee, Elisa T.;Mosley, Thomas H., Jr.;Weder, Alan;Roman, Mary J.
对于BSA：2.423+（年龄[岁]*0.009）+（bsa [m2]*0.461）-（性别[1=男性，2=女性]*.267）SEE = 0.261 cm身高：1.519+（年龄[岁]*0.010）+（ht [cm]*.010）-（性别[1=男性，2=女性]*.247）SEE = 0.215 cm。在广泛的年龄范围内，预测体表面积（BSA）正常主动脉根部直径的列线图已被广泛使用，但由于缺乏对性别影响的考虑、年龄层之间主动脉直径上限的跳跃以及来自年龄较大的青少年的数据而受到限制。根据美国超声心动图协会惯例，在来自临床或基于人群的样本中，对体重正常、无高血压、无糖尿病且年龄≥15岁且无主动脉瓣疾病的个体测量主动脉窦直径。协方差分析和线性回归与残差评估确定的决定因素，并制定了正常主动脉根部直径的预测模型。在1，207例≥15岁的明显正常个体（54%为女性）中，主动脉根部直径为2.1至4.3 cm。主动脉根部直径与BSA和身高（均r=0.48）、年龄（r=0.36）和男性性别（根据BSA和年龄调整+2.7 mm）密切相关（均p<0.001）。使用年龄、性别和BSA或身高的多变量方程强烈预测主动脉直径（R=0.674，p <0.001），残差与年龄或体型的关系最小：总之，男性主动脉根部直径较大，并随体型和年龄增加而增加。回归模型包括身体大小，年龄和性别适用于青少年和成人没有以前的诺模图的限制。
for BSA: 2.423+(age [yrs]*0.009) + (bsa [m2]*0.461) -(sex [1=M, 2=F]*.267) SEE = 0.261 cm for height: 1.519+(age [yrs]*0.010) + (ht [cm]*.010)-(sex [1=M, 2=F]*.247) SEE = 0.215 cm. Nomograms to predict normal aortic root diameter for body surface area (BSA) in broad ranges of age have been widely used, but are limited by lack of consideration of gender effects, jumps in upper limits of aortic diameter between age strata, and data from older teenagers. Sinuses of Valsalva diameter was measured by American Society of Echocardiography convention in normal-weight, non-hypertensive, non-diabetic individuals ≥15 years old without aortic valve disease from clinical or population-based samples. Analyses of covariance and linear regression with assessment of residuals identified determinants and developed predictive models for normal aortic root diameter. Among 1,207 apparently normal individuals ≥15 years old (54% female), aortic root diameter was 2.1 to 4.3 cm. Aortic root diameter was strongly related to BSA and height (both r=0.48), age (r=0.36) and male gender (+2.7 mm adjusted for BSA and age) (all p<0.001). Multivariable equations using age, gender, and either BSA or height predicted aortic diameter strongly (both R=0.674, p <0.001) with minimal relation of residuals to age or body size: In conclusion, aortic root diameter is larger in men and increases with body size and age. Regression models incorporating body size, age and gender are applicable to adolescents and adults without limitations of previous nomograms.
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影响因子：
2.8
作者：
Gautier, Mathieu;Detaint, Delphine;Jondeau, Guillaume
通讯作者：
Jondeau, Guillaume
影响因子：
--
作者：
Du Bois, D;Du Bois, EF
通讯作者：
Du Bois, EF
影响因子：
37.8
作者：
VASAN, RS;LARSON, MG;LEVY, D
通讯作者：
LEVY, D
DOI：
10.1016/j.echo.2008.02.006
发表时间：
2008-08-01
影响因子：
6.5
作者：
Pettersen, Michael D.;Du, Wei;Humes, Richard A.
通讯作者：
Humes, Richard A.
影响因子：
2.8
作者：
ROMAN, MJ;DEVEREUX, RB;ROBINS, J
通讯作者：
ROBINS, J