Self-shrinking soft demoulding for complex high-aspect-ratio microchannels.

Self-shrinking soft demoulding for complex high-aspect-ratio microchannels.
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复杂高深宽比微通道的自收缩软脱模

DOI:
10.1038/s41467-022-32859-z
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发表时间:
2022-08-29
影响因子:
16.6
通讯作者:
Qin, Peiwu
Qin, Peiwu
中科院分区:
综合性期刊1区
文献类型:
--
作者:
Fan, Dongliang;Yuan, Xi;Wu, Wenyu;Zhu, Renjie;Yang, Xin;Liao, Yuxuan;Ma, Yunteng;Xiao, Chufan;Chen, Cheng;Liu, Changyue;Wang, Hongqiang;Qin, Peiwu

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微通道是动物、植物和各种人工设备(如软机器人、可穿戴传感器和芯片上器官)的基本元素。然而,具有复杂几何形状和高纵横比的三维(3D)微通道仍然具有挑战性,通过常规方法,如软光刻,模板溶解,和基质溶胀过程中产生,虽然它们在自然界中是广泛的。在这里,我们提出了一个简单的和无溶剂的制造方法,能够生产具有复杂的三维结构,长的长度,和小直径的单片微通道。在脱模过程中引入了软模板和以剥离为主的模板去除工艺,简称软脱模。结合热拉伸技术,可以生成具有小直径(10 µm)、高纵横比(6000,长度与直径之比)和复杂3D几何形状的微通道。我们展示了该技术在多个场景中的广泛适用性和重大影响,包括软机器人,可穿戴传感器,软天线和人造血管。微通道是人工器件设计的基本要素,但具有复杂几何形状和高纵横比的三维(3D)微通道的制造仍然具有挑战性。在这里,作者展示了一种简单且无溶剂的制造方法,能够生产具有复杂3D结构、长长度和小直径的单片微通道。
Microchannels are the essential elements in animals, plants, and various artificial devices such as soft robotics, wearable sensors, and organs-on-a-chip. However, three-dimensional (3D) microchannels with complex geometry and a high aspect ratio remain challenging to generate by conventional methods such as soft lithography, template dissolution, and matrix swollen processes, although they are widespread in nature. Here, we propose a simple and solvent-free fabrication method capable of producing monolithic microchannels with complex 3D structures, long length, and small diameter. A soft template and a peeling-dominant template removal process are introduced to the demoulding process, which is referred to as soft demoulding here. In combination with thermal drawing technology, microchannels with a small diameter (10 µm), a high aspect ratio (6000, length-to-diameter), and intricate 3D geometries are generated. We demonstrate the vast applicability and significant impact of this technology in multiple scenarios, including soft robotics, wearable sensors, soft antennas, and artificial vessels. Microchannels are the essential elements for the design of artificial devices but the fabrication of three dimensional (3D) microchannels with complex geometry and a high aspect ratio remains challenging. Here, the authors demonstrate a simple and solvent-free fabrication method capable of producing monolithic microchannels with complex 3D structures, long length, and small diameter.
基于液体模板的喷墨打印微通道
DOI: 10.1039/c4lc01486c
发表时间: 2015-01-01
期刊: LAB ON A CHIP
影响因子: 6.1
作者:
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DOI: 10.1126/science.aav9750
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期刊: Science (New York, N.Y.)
影响因子: --
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发表时间: 2014-08-01
影响因子: 46.9
作者:
Bhatia, Sangeeta N.;Ingber, Donald E.
通讯作者: Ingber, Donald E.
DOI: 10.1016/j.matdes.2015.05.012
发表时间: 2015-09-15
期刊: MATERIALS & DESIGN
影响因子: 8.4
作者:
Li, Gang;Xu, Shengyong
通讯作者: Xu, Shengyong
DOI: 10.1021/ac9912294
发表时间: 2000-07-15
影响因子: 7.4
作者:
Anderson, JR;Chiu, DT;Whitesides, GM
通讯作者: Whitesides, GM