History for some or lesson for all? A systematic review and meta-analysis on the immediate and long-term mental health impact of the 2002-2003 Severe Acute Respiratory Syndrome (SARS) outbreak.
History for some or lesson for all? A systematic review and meta-analysis on the immediate and long-term mental health impact of the 2002-2003 Severe Acute Respiratory Syndrome (SARS) outbreak.
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DOI：
10.1186/s12889-021-10701-3
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发表时间：
2021-04-07
影响因子：
4.5
通讯作者：
Phiri P
中科院分区：
文献类型：
--
作者：
Chau SWH;Wong OWH;Ramakrishnan R;Chan SSM;Wong EKY;Li PYT;Raymont V;Elliot K;Rathod S;Delanerolle G;Phiri P
本系统综述和荟萃分析的目的是检查SARS患者、医护人员和SARS疫区公众中短期和长期不良心理健康结果的患病率，并检查与这些心理健康结果相关的保护因素和风险因素。我们使用Medline、Pubmed、Embase、PsycInfo、Web of Science Core Collection、CNKI、国家中央图书馆在线目录和论文数据库等数据库对文献进行了系统检索，以确定2003年1月至2020年5月期间发表的英文或中文研究，这些研究报告了SARS主要爆发地区SARS患者、医护人员和公众的心理困扰和心理健康发病率。文献检索产生了6984个标题。筛选共纳入80篇论文，其中35篇纳入meta分析。SARS幸存者中康复后可能或临床诊断的焦虑障碍、抑郁障碍和创伤后应激障碍（PTSD）的患病率分别为19%、20%和28%。在出院后6个月内和6个月以上进行的研究中，这些结果的患病率没有显著差异。SARS幸存者在出院后6个月后，与精神健康有关的生活质量测量的某些方面仍然受损。sars后医护人员中可能的抑郁症和创伤后应激障碍患病率分别为12%和11%。在SARS期间，普通公众的焦虑水平有所增加，但是否对整个人群的心理健康有临床意义的影响仍然没有定论。叙事综合显示，职业接触SARS患者和感知到的污名化是医护人员不良心理健康结果的风险因素，但由于研究的局限性，无法确定因果关系。SARS幸存者的慢性精神疾病应该提醒我们注意covid-19患者潜在的长期精神健康并发症。在高风险场所工作的卫生保健工作者应得到充分的精神卫生支持。应探讨和解决对患者和卫生保健工作者的歧视问题。纳入研究的显著偏倚风险和高度异质性限制了本综述证据体的确定性。在线版本包含补充材料，可在10.1186/s12889-021-10701-3获得。
The aims of this systematic review and meta-analysis are to examine the prevalence of adverse mental health outcomes, both short-term and long-term, among SARS patients, healthcare workers and the general public of SARS-affected regions, and to examine the protective and risk factors associated with these mental health outcomes. We conducted a systematic search of the literature using databases such as Medline, Pubmed, Embase, PsycInfo, Web of Science Core Collection, CNKI, the National Central Library Online Catalog and dissertation databases to identify studies in the English or Chinese language published between January 2003 to May 2020 which reported psychological distress and mental health morbidities among SARS patients, healthcare workers, and the general public in regions with major SARS outbreaks. The literature search yielded 6984 titles. Screening resulted in 80 papers for the review, 35 of which were included in the meta-analysis. The prevalence of post-recovery probable or clinician-diagnosed anxiety disorder, depressive disorder, and post-traumatic stress disorder (PTSD) among SARS survivors were 19, 20 and 28%, respectively. The prevalence of these outcomes among studies conducted within and beyond 6 months post-discharge was not significantly different. Certain aspects of mental health-related quality of life measures among SARS survivors remained impaired beyond 6 months post-discharge. The prevalence of probable depressive disorder and PTSD among healthcare workers post-SARS were 12 and 11%, respectively. The general public had increased anxiety levels during SARS, but whether there was a clinically significant population-wide mental health impact remained inconclusive. Narrative synthesis revealed occupational exposure to SARS patients and perceived stigmatisation to be risk factors for adverse mental health outcomes among healthcare workers, although causality could not be determined due to the limitations of the studies. The chronicity of psychiatric morbidities among SARS survivors should alert us to the potential long-term mental health complications of covid-19 patients. Healthcare workers working in high-risk venues should be given adequate mental health support. Stigmatisation against patients and healthcare workers should be explored and addressed. The significant risk of bias and high degree of heterogeneity among included studies limited the certainty of the body of evidence of the review. The online version contains supplementary material available at 10.1186/s12889-021-10701-3.
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影响因子：
11.8
作者：
Hawryluck L;Gold WL;Robinson S;Pogorski S;Galea S;Styra R
通讯作者：
Styra R
影响因子：
4
作者：
Cheung, Y. T.;Chau, P. H.;Yip, Paul S. F.
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影响因子：
105.7
作者：
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通讯作者：
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影响因子：
4.5
作者：
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通讯作者：
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