Prediction and Measurement of the Size of Thermal Lesion Induced by High Intensity Focused Ultrasound in a Tissue-Mimicking Phantom
Prediction and Measurement of the Size of Thermal Lesion Induced by High Intensity Focused Ultrasound in a Tissue-Mimicking Phantom
复制标题
模拟组织模型中高强度聚焦超声引起的热损伤大小的预测和测量
DOI：
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发表时间：
2009
期刊：
影响因子：
--
通讯作者：
M. Choi
中科院分区：
文献类型：
--
作者：
K. Lee;M. Choi
基于线性声学理论，预测了高强度聚焦超声(HIFU)在模拟组织体模中引起的热损伤大小。预测了HIFU的强焦场，并计算了体模中产生的温度场。根据病灶周围240min(43℃)的热剂量边界，估算热剂量分布，确定热损伤大小。采用孔径半径为35.0 mm、焦距为62.6 mm、中心频率为1.1 MHz的凹形聚焦换能器，将不同峰值正焦压力下HIFU对病灶大小的预测与HIFU照射下的热损伤实验测量结果进行了比较。结果表明，随着焦压的变化，预测值与实测值基本吻合。
Based on a linear acoustic theory, the size of thermal lesion induced by high intensity focused ultrasound (HIFU) in a tissue-mimicking phantom was predicted. The strong focal field of HIFU was predicted and the resulting temperature field in the phantom was calculated. The thermal dose distribution was estimated and the size of thermal lesion was determined based on the evaluation of the 240 min (at 43 °C) thermal dose boundary around the focus. The prediction of the lesion size with different peak positive focal pressures of HIFU was compared with the experimental measurement on thermal lesions visualized in an optically transparent polyacrylamide hydrogel tissue-mimicking phantom exposed to HIFU, using a concave focused transducer with an aperture radius of 35.0 mm, a focal length of 62.6 mm, and a center frequency of 1.1 MHz. It was shown that the prediction characteristically agreed with the measurement as the focal pressure varies.
影响因子：
2.4
作者：
DAMIANOU, C;HYNYNEN, K
通讯作者：
HYNYNEN, K
影响因子：
2.4
作者：
Khokhlova, VA;Bailey, MR;Crum, LA
通讯作者：
Crum, LA
DOI：
10.1016/0360-3016(84)90379-1
发表时间：
1984-01-01
影响因子：
7
作者：
SAPARETO, SA;DEWEY, WC
通讯作者：
DEWEY, WC