Production of salvianolic acid B in roots of Salvia miltiorrhiza (Danshen) during the post-harvest drying process.

Production of salvianolic acid B in roots of Salvia miltiorrhiza (Danshen) during the post-harvest drying process.
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丹参采后干燥过程中丹酚酸B的产生

DOI:
10.3390/molecules17032388
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发表时间:
2012-02-27
期刊:
Molecules (Basel, Switzerland)
影响因子:
--
通讯作者:
Zhou TS
Zhou TS
中科院分区:
其他
文献类型:
--
作者:
Li XB;Wang W;Zhou GJ;Li Y;Xie XM;Zhou TS

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干燥是药用植物采后加工中最常见和最基本的步骤,有助于提高药用植物的质量和价值。但是,对这方面的关注和研究工作相对较少。研究了丹参(Salvia miltiorrhiza,Dashen)根在不同烘箱温度下干燥过程中,丹参酸B(SaB)、二氢丹参酮I、隐丹参酮、丹参酮I和丹参酮IIA等5种主要活性成分含量的动态变化。在新鲜物料中发现少量的SaB,而在50~160 °C干燥时检测到SaB的显著增加。在130 °C干燥40 min后达到最大值,其变化呈倒V型曲线。SaB的产生与干燥温度呈显著正相关,与样品水分呈显著负相关。丹参酮含量在干燥初期增加近一倍,其变化趋势与干燥温度和样品含水量的变化趋势相似。这些结果支持了我们的推测,即采后的新鲜植物材料,特别是根,仍然是生理活性器官,并会表现出一系列的抗脱水机制,包括在脱水早期产生相关的次生代谢产物。因此,合理设计干燥工艺有助于提高而不是降低丹参和其他类似药用植物的质量。
Drying is the most common and fundamental procedure in the post-harvest processing which contributes to the quality and valuation of medicinal plants. However, attention to and research work on this aspect is relatively poor. In this paper, we reveal dynamic variations of concentrations of five major bioactive components, namely salvianolic acid B (SaB), dihydrotanshinone I, cryptotanshinone, tanshinone I and tanshinone IIA, in roots of Salvia miltiorrhiza (Dashen) during the drying process at different oven temperatures. A minor amount of SaB was found in fresh materials while an noticeable increase in SaB was detected in drying at 50~160 °C. The maximal value occured after 40 min of drying at 130 °C and its variation showed a reverse V-shaped curve. Production of SaB exhibited a significant positive correlation with drying temperatures and a significant negative correlation with sample moistures. The amounts of tanshinones were nearly doubled in the early stage of drying and their variations showed similar changing trends with drying temperatures and sample moistures. The results supported our speculation that postharvest fresh plant materials, especially roots, were still physiologically active organs and would exhibit a series of anti-dehydration mechanisms including production of related secondary metabolites at the early stage of dehydration. Hence, the proper design of drying processes could contribute to promoting rather than reducing the quality of Danshen and other similar medicinal plants.
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