Vaccines and photodynamic therapies for oral microbial-related diseases.

Vaccines and photodynamic therapies for oral microbial-related diseases.
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DOI:
10.2174/138920009787048365
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发表时间:
2009-01
影响因子:
2.3
通讯作者:
Huang CM
Huang CM
中科院分区:
医学4区
文献类型:
--
作者:
Liu PF;Zhu WH;Huang CM

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口腔是各种细菌的有利栖息地。牙菌斑的微生物组成是人类各种口腔疾病的常见原因,包括龋齿、牙周病和口臭。一般来说,口腔抗菌剂如抗生素通常用于治疗口腔细菌感染。传统的牙周手术既痛苦又耗时。此外,细菌耐药性和抗生素的毒性已成为全球性的大流行和不可避免的。近年来,龋病和牙周病的疫苗已被开发和应用。此外,光动力疗法的使用已成为抗生素药物的替代品。本文的目的是强调疫苗治疗和光动力治疗口腔微生物相关疾病的优势相比,抗菌药物和传统的牙周手术治疗。
The mouth is a favorable habitat for a great variety of bacteria. Microbial composition of dental plaque is the usual cause of various oral diseases in humans, including dental caries, periodontal disease and halitosis. In general, oral antibacterial agents such as antibiotics are commonly used to treat oral bacterial infection. Traditional periodontal surgery is painful and time-consuming. In addition, bacterial resistance and toxicity of antibiotics have become a global pandemic and unavoidable. Recently, vaccines for dental caries and periodontal disease have been developed and applied. Moreover, the use of photodynamic therapy has become an alternative to antibiotic drugs. The purpose of this article is to highlight the advantages of vaccine therapy and photodynamic therapy for oral microbial-related diseases compared to treatments with antimicrobial agents and traditional periodontal surgery.
DOI: 10.1902/jop.1992.63.4s.338
发表时间: 1992-04-01
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