The functional architecture for face-processing expertise: FMRI evidence of the developmental trajectory of the core and the extended face systems.
The functional architecture for face-processing expertise: FMRI evidence of the developmental trajectory of the core and the extended face systems.
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DOI：
10.1016/j.neuropsychologia.2013.08.005
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发表时间：
2013-11
期刊：
影响因子：
2.6
通讯作者：
Stiles, Joan
中科院分区：
文献类型：
--
作者：
Haist, Frank;Adamo, Maha;Wazny, Jarnet Han;Lee, Kang;Stiles, Joan
关键词：
处理面孔的专长是人类社会交往的基石。然而，许多关键的大脑区域的发展过程中，支持人脸优先处理在人类大脑仍然不确定。在这里，我们目前的研究结果从功能磁共振成像研究中使用一个简单的观看范式的面孔和对象在一个连续的年龄范围从6岁到成年的样本。这些发现是第一次使用这样的样本与全脑功能磁共振成像分析配对，以研究从童年中期到成年期整个发展谱中的核心和扩展面部网络的发展。我们发现的证据，虽然温和，在右侧梭状面区（rFFA）的体积的发展趋势，但没有发展变化的激活强度。从空间的角度来看，最常见的面部处理成人研究中发现的右侧梭状回的中间部分越来越有可能被列入FFA随着年龄的增长到成年。在FFA之外，最引人注目的发现是，儿童相对于成人而言，面部扩展系统的几乎所有方面都处于过度激活状态，包括杏仁核、前颞极、前额叶、额下回、前扣带回和顶叶皮层。总的来说，研究结果表明，发展的最佳特征是增加整个大脑中面部敏感区域的调制，以仅参与任务要求所必需的那些系统。
Expertise in processing faces is a cornerstone of human social interaction. However, the developmental course of many key brain regions supporting face preferential processing in the human brain remains undefined. Here, we present findings from an FMRI study using a simple viewing paradigm of faces and objects in a continuous age sample covering the age range from 6 years through adulthood. These findings are the first to use such a sample paired with whole-brain FMRI analyses to investigate development within the core and extended face networks across the developmental spectrum from middle childhood to adulthood. We found evidence, albeit modest, for a developmental trend in the volume of the right fusiform face area (rFFA) but no developmental change in the intensity of activation. From a spatial perspective, the middle portion of the right fusiform gyrus most commonly found in adult studies of face processing was increasingly likely to be included in the FFA as age increased to adulthood. Outside of the FFA, the most striking finding was that children hyperactivated nearly every aspect of the extended face system relative to adults, including the amygdala, anterior temporal pole, insula, inferior frontal gyrus, anterior cingulate gyrus, and parietal cortex. Overall, the findings suggest that development is best characterized by increasing modulation of face-sensitive regions throughout the brain to engage only those systems necessary for task requirements.
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