Identifying Perceived Barriers to Human Papillomavirus Vaccination as a Preventative Strategy for Cervical Cancer in Nigeria.
Identifying Perceived Barriers to Human Papillomavirus Vaccination as a Preventative Strategy for Cervical Cancer in Nigeria.
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DOI：
10.5334/aogh.2890
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发表时间：
2020-09-17
影响因子：
2.9
通讯作者：
Brock T
中科院分区：
文献类型：
--
作者：
Nguyen NY;Okeke E;Anglemyer A;Brock T
发展中国家的宫颈癌死亡率高得不成比例，这是当今存在的最严重的健康差距之一，是尼日利亚妇女中第二常见的癌症。人乳头瘤病毒(HPV)疫苗作为主要预防策略在尼日利亚并未得到广泛应用。这项研究调查了尼日利亚社区对HPV疫苗接种的障碍，目标是卫生工作者的看法。这项描述性研究收集了尼日利亚阿南布拉州成年卫生工作者的横断面、便利样本的反应。本研究以计划行为模型理论为基础，结合前人的研究成果，编制了具有多个效度量表的42项匿名问卷。这项自行管理的调查是由研究助理在阿南布拉州的研究地点分发的，这些研究地点是由阿达齐-阿尼、奥尼沙和奥卡地区通过当地选民确定的。数据分析采用Microsoft Excel软件进行描述性统计，R软件进行Logistic回归分析，统计学意义水平为5%。对基线知识问卷进行分组分析，以确定是否存在基于人口学特征的正确回答的差异，例如：机构类型、职业、年龄、性别、宗教和父母状况。答复来自137名尼日利亚卫生工作者、44%的护士、14%的医生、6%的药剂师和31%的其他卫生工作者。大多数受访者是女性(69%)，年龄在18岁到39岁之间(78%)，来自城市(82%)，并被确认为有基督教宗教信仰(97%)。确定的最大障碍是缺乏认识(39%)、疫苗可获得性(39%)和费用(13%)。当被问及有关HPV的基线知识问题时，与男性相比，女性更有可能回答错误。在以下陈述中发现了显著的差异：(1)人乳头瘤病毒是性传播的(p=0.008)；(2)人乳头瘤病毒是一种仅影响女性的感染(p=0.004)。尼日利亚卫生工作者确定的HPV疫苗接种的公认障碍包括缺乏认识、疫苗可获得性/可及性、成本以及对可接受性的担忧。正在进行的补贴疫苗费用的努力、提高对HPV疫苗认识的运动以及改善可及性的干预措施可能会提高尼日利亚的接种率，并最终提高该人群中因宫颈癌而导致的死亡率。
Cervical cancer deaths are disproportionately higher in developing countries depicting one of the most profound health disparities existing today and is ranked as the second most frequent cancer among women in Nigeria. The Human Papillomavirus (HPV) vaccine as a primary prevention strategy is not widely used in Nigeria. This study investigated perceived barriers to HPV vaccination in a Nigerian community, targeting health workers’ perceptions. This descriptive study captured responses from a cross-sectional, convenience sample of adult health workers within Anambra State, Nigeria. An anonymous 42-item survey with multiple validated scales was developed based on the Theory of Planned Behavior model and previous studies. The self-administered survey was distributed by research assistants at study sites within Anambra State which were identified through local constituents by the regional zones Adazi-Ani, Onitsha, and Awka. Data analyses were performed using Microsoft Excel for descriptive statistics and R software for the logistic regression, with a statistical significance level of 5%. Subgroup analysis was performed for the baseline knowledge questionnaire to determine if there were any differences in correct responses based on demographics such as: Institution type, profession, age, sex, religion and parental status. Responses were collected from 137 Nigerian health workers; 44% nurses, 14% physicians, 6% pharmacists and 31% other health workers. The majority of respondents were female (69%), between 18 and 39 years of age (78%), from urban settings (82%), and identified as having Christian religious beliefs (97%). The most significant barriers identified were lack of awareness (39%), vaccine availability (39%), and cost (13%). When asked baseline knowledge questions regarding HPV, females were more likely to answer incorrectly as compared to males. Significant differences were found for statements: (1) HPV is sexually transmitted (p = 0.008) and (2) HPV is an infection that only affects women (p = 0.004). Perceived barriers to HPV vaccination identified by Nigerian health workers include lack of awareness, vaccine availability/accessibility, cost, and concerns about acceptability. Ongoing efforts to subsidize vaccine costs, campaigns to increase awareness of HPV vaccine, and interventions to improve attainability could advance administration rates in Nigeria, and ultimately improve death rates due to cervical cancer in this population.
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影响因子：
2.7
作者：
Godin, G;Kok, G
通讯作者：
Kok, G
DOI：
10.1080/0144361021000043272
发表时间：
2003-01-01
期刊：
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology
影响因子：
--
作者：
Ayinde, O A;Omigbodun, A O
通讯作者：
Omigbodun, A O
DOI：
10.1186/s12962-016-0057-0
发表时间：
2016
期刊：
Cost effectiveness and resource allocation : C/E
影响因子：
--
作者：
Umeh IB;Nduka SO;Ekwunife OI
通讯作者：
Ekwunife OI
影响因子：
7.8
作者：
Black E;Richmond R
通讯作者：
Richmond R
影响因子：
5.5
作者：
Prislin, R;Nader, PR;Sawyer, MH
通讯作者：
Sawyer, MH