Optical projection angiography
Optical projection angiography
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光学投影血管造影
DOI：
10.1063/1.4967219
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发表时间：
2016-11
影响因子：
4
通讯作者：
曾亚光
中科院分区：
文献类型：
--
作者：
廖日威;王茗祎;张富丽;韩定安;王瑞康;杨国建;曾亚光
We propose the optical projection angiography (OPA) based on lateral dynamic scattering light for visualizing a three-dimensional (3D) blood-flow network. In OPA, a pulsed laser source illuminates a live biological sample for eliminating digital camera integration effects. The 2D flow image can be obtained by separating the dynamic and static scattering light signal of each camera pixel in the frequency domain. Flow images at a different angle are combined to reconstruct the 3D volume of the sample to realize OPA. Moreover, as our experiment retains the bright-field optical projection tomography (OPT) setup, the OPA image for the circulatory system and the OPT image for the skeletal structure can simultaneously be reconstructed. The experimental results can potentially be applied in physiological development studies.
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