Human investigations into the arterial and cardiopulmonary baroreflexes during exercise.
Human investigations into the arterial and cardiopulmonary baroreflexes during exercise.
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DOI：
10.1113/expphysiol.2011.057554
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发表时间：
2012-01
影响因子：
2.7
通讯作者：
Raven PB
中科院分区：
文献类型：
--
作者：
Fadel PJ;Raven PB
经过相当多的争论和关键的实验证据，动脉压力感受器反射的重要性，有助于和维持适当的神经心血管调节运动，现在是公认的。事实上，动脉压力反射在运动期间以强度依赖性方式重置，以继续像休息时一样有效地调节血压。研究表明，动脉压力感受器反射的运动重调定是由中枢指令的前馈机制和与骨骼肌传入相关的反馈机制（运动升压反射）共同介导的。另一个可能不太受重视的神经机制涉及唤起和维持对运动的神经心血管反应是心肺压力反射。有限的信息提供了关于心肺压力感受器反射在运动过程中的作用，介导交感神经活动和血压反应的证据。此外，最近的研究表明，心肺压力感受器和动脉压力反射之间的相互作用，在动态运动，这有助于运动引起的血压升高的幅度，以及重置动脉压力反射。此外，来自心肺压力感受器的神经输入似乎在建立动脉压力感受器反射的工作点中起重要作用。本次研讨会的审查将突出这些重要领域的最新研究表明，四个神经机制（中央命令，运动加压反射，动脉压力反射和心肺压力反射）的相互作用是不可或缺的调解神经心血管调整运动。
After considerable debate and key experimental evidence, the importance of the arterial baroreflex in contributing to and maintaining the appropriate neural cardiovascular adjustments to exercise is now well accepted. Indeed, the arterial baroreflex resets during exercise in an intensity-dependent manner to continue to regulate blood pressure as effectively as at rest. Studies have indicated that the exercise resetting of the arterial baroreflex is mediated by both the feed-forward mechanism of central command and the feed-back mechanism associated with skeletal muscle afferents (the exercise pressor reflex). Another perhaps less appreciated neural mechanism involved in evoking and maintaining neural cardiovascular responses to exercise is the cardiopulmonary baroreflex. The limited information available regarding the cardiopulmonary baroreflex during exercise provides evidence for a role in mediating sympathetic nerve activity and blood pressure responses. In addition, recent investigations have demonstrated an interaction between cardiopulmonary baroreceptors and the arterial baroreflex during dynamic exercise, which contributes to the magnitude of exercise-induced increases in blood pressure as well as the resetting of the arterial baroreflex. Furthermore, neural inputs from the cardiopulmonary baroreceptors appear to play an important role in establishing the operating point of the arterial baroreflex. This symposium review will highlight recent studies in these important areas indicating that the interactions of four neural mechanisms (central command, the exercise pressor reflex, the arterial baroreflex and cardiopulmonary baroreflex) are integral in mediating the neural cardiovascular adjustments to exercise.
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影响因子：
6.7
作者：
Carrington, CA;White, MJ
通讯作者：
White, MJ
DOI：
10.1152/ajpheart.1997.272.3.h1157
发表时间：
1997-03-01
影响因子：
4.8
作者：
Iellamo, F;Legramante, JM;Peruzzi, G
通讯作者：
Peruzzi, G
DOI：
10.1111/j.1748-1716.1977.tb10383.x
发表时间：
1977-01-01
期刊：
ACTA PHYSIOLOGICA SCANDINAVICA
影响因子：
--
作者：
BEVEGARD, S;CASTENFORS, J;TRANESJO, J
通讯作者：
TRANESJO, J
影响因子：
3.3
作者：
Cui, J;Wilson, TE;Crandall, CG
通讯作者：
Crandall, CG
影响因子：
15.9
作者：
BEVEGARD, BS;SHEPHERD, JT
通讯作者：
SHEPHERD, JT