Information processing during phagocytosis.
Information processing during phagocytosis.
复制标题
吞噬作用期间的信息处理。
DOI：
10.1038/nri3244
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发表时间：
2012-06-15
期刊：
影响因子：
--
通讯作者：
Goodridge HS
中科院分区：
文献类型：
--
作者：
Underhill DM;Goodridge HS
Phagocytosis, the process by which macrophages, dendritic cells and other myeloid phagocytes internalize diverse particulate targets, is a key mechanism of innate immunity. The molecular and cellular events underlying the binding and engulfment of targets in phagosomes have been extensively studied. More recent data suggest that the process of phagocytosis itself provides information to myeloid phagocytes about the nature of the targets they are eating and that this helps tailor inflammatory responses. In this Review, we discuss how such information is acquired during phagocytosis, and how it is processed to coordinate an immune response.
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DOI：
10.1084/jem.20021890
发表时间：
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期刊：
The Journal of experimental medicine
影响因子：
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