Salmonella and Shigella and antimicrobial susceptibility profiles among adult patients with complaints of diarrhea at Hawassa comprehensive specialized hospital, Hawassa, Ethiopia.

Salmonella and Shigella and antimicrobial susceptibility profiles among adult patients with complaints of diarrhea at Hawassa comprehensive specialized hospital, Hawassa, Ethiopia.
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埃塞俄比亚阿瓦萨综合专科医院成人腹泻患者的沙门氏菌和志贺氏菌及抗菌药物敏感性分析

DOI:
10.1177/20503121211000911
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发表时间:
2021
期刊:
影响因子:
2.3
通讯作者:
Ali MM
Ali MM
中科院分区:
其他
文献类型:
--
作者:
Abera K;Anticho TL;Ali MM

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腹泻是发展中国家公共卫生的重要疾病之一。在腹泻的病原体中,沙门氏菌血清型和志贺氏菌属继续在资源有限的国家发挥主要作用。本研究的目的是评估沙门氏菌和志贺氏菌的患病率,危险因素和抗生素敏感性的投诉腹泻的成年患者。2019年3月至2019年11月,在Hawassa大学综合专科医院的腹泻成人患者中进行了一项基于医院的横断面研究。采用结构式问卷调查收集参与者的社会人口学、行为和环境特征。将粪便样品接种到亚硒酸盐F肉汤和木糖赖氨酸葡萄糖培养基上,以分离沙门氏菌血清型和志贺氏菌属。药敏试验采用Kirby-Bauer法。数据分析采用SPSS 20软件包。双变量和多变量分析用于确定因变量和自变量之间的关联。沙门氏菌血清型和志贺菌属的总体患病率为8.6%,95%置信区间(3.2-13.8)。那些不洗手的人感染沙门氏菌和志贺氏菌的可能性是他们的同伴的三倍(p < 0.001)。食用未煮熟食物的参与者感染沙门氏菌和志贺氏菌的机会约为他们的同行的两倍(p < 0.001)。沙门氏菌和志贺菌的所有血清型均对氨苄青霉素耐药。在这项研究中,相对较高的流行沙门氏菌血清型和志贺氏菌物种被发现在成人腹泻的投诉在哈瓦萨大学综合专科医院。食用未煮熟的食物和不洗手与沙门氏菌和志贺氏菌的流行显著相关。
Diarrhea is one of the public health important diseases in developing countries. Among the causative agents of diarrhea, Salmonella serovars and Shigella species continue to play a major role in resource-limited countries. The aim of this study was to assess the prevalence of Salmonella and Shigella, risk factors, and antimicrobial susceptibility profiles among adult patients with complaints of diarrhea. A hospital-based cross-sectional study was conducted among adult patients with complaints of diarrhea at Hawassa University Comprehensive Specialized Hospital from March 2019 to November 2019. A structured questionnaire was used to collect sociodemographic, behavioral, and environmental characteristics of participants. Fecal samples were inoculated onto Selenite F broth and Xylose Lysine Dextrose media to isolate Salmonella serovars and Shigella species. Antibiotic susceptibility testing was performed by the Kirby-Bauer method. Data were analyzed by SPSS computer software version 20. Bivariate and multivariable analysis was used to determine the association between dependent and independent variables. The overall prevalence of Salmonella serovars and Shigella species was 8.6% with 95% confidence interval (3.2–13.8). Participant those who do not wash their hands were three times more likely to be infected with Salmonella and Shigella (p < 0.001) than their counterparts. Participants who consume uncooked food had about two times the chance to be infected with Salmonella and Shigella (p < 0.001) than their counterparts. All serovars of Salmonella and serotypes of Shigella were resistant to ampicillin. In this study, relatively a high prevalence of Salmonella serovars and Shigella species was found among adult patients with complaints of diarrhea at Hawassa University Comprehensive Specialized Hospital. Consuming uncooked food and not washing hands were significantly associated with the prevalence of Salmonella and Shigella.
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