Short-term variablility of respiration and sleep during unattended nonlaboratory polysomnogaphy - The sleep heart health study
Short-term variablility of respiration and sleep during unattended nonlaboratory polysomnogaphy - The sleep heart health study
复制标题
无人值守的非实验室多导睡眠监测期间呼吸和睡眠的短期变异性 - 睡眠心脏健康研究
作者：
Stuart F. Quan;Michael E. Griswold;C. Iber;F. Nieto;David M. Rapoport;S. Redline;M. Sanders;T. Young
研究目的：确定间隔数月的无人值守非实验室多导睡眠监测2晚期间呼吸和睡眠指标的短期变异性。设计：采用分层设计随机选择受试者，初步估计2个标准：呼吸紊乱指数[RDI3%(呼吸暂停或低呼吸事件与>；3%O2减饱和相关)：85%]。比较首次多导睡眠图和重复多导睡眠图的RDI和睡眠数据。地点：NA参与者：99名睡眠心脏健康研究参与者的子集，他们同意在最初研究的4个月内进行重复多导睡眠图检查。干预：NA测量和结果：91名受试者获得了可接受的重复多导睡眠图(平均研究间隔：77±18{SD}天；范围：31~112天)。在使用包括RDI3%和RDI4%(与≥4%O2减饱和相关的呼吸暂停或低呼吸事件)在内的几种不同RDI定义的研究夜晚之间，RDI值没有显著的偏差。使用组内相关性(ICC)估计的研究之间的变异性在0.77到0.81之间。对于RDI值为3%和15的受试者，变异性随RDI值的增加而增加，但对于RDI值为3%≥15的受试者，变异性是恒定的。体重指数、社会功能、性别或年龄不能直接预测RDI的变异性。以≤5、≤10和≤15每小时睡眠事件的RDI4%为切点，分别有791%、85.7%和87.9%的受试者在两个研究晚上具有相同的SDB状态分类。研究之间在睡眠分期、睡眠效率或唤醒指数方面也没有明显的偏差。然而，变异更大，ICC值从0.37(快速眼动时间百分比)到0.76(觉醒指数)。结论：在睡眠心脏健康研究中，通过一晚无人值守的非实验室多导睡眠图可以准确估计睡眠障碍呼吸的严重程度和睡眠质量。只要遵循类似的记录技术和质量保证程序，这些发现可能适用于其他大型流行病学研究。
Study Objectives: To determine the short-term variability of indices of disturbed respiration and sleep during 2 nights of unattended nonlaboratory polysomnography conducted several months apart. Design: Participants were randomly selected using a block design with stratification on preliminary estimates of 2 criteria: respiratory disturbance index [RDI 3% (apnea or hypopnea events associated with > 3% O 2 desaturation): 85%). The RDI and sleep data from initial and repeated polysomnography were compared. Setting: NA Participants: A subset of 99 participants in the Sleep Heart Health Study who agreed to have a repeat polysomnogram within 4 months of their original study. Interventions: NA Measurements and Results: Acceptable repeat polysomnograms were obtained in 91 subjects (mean study interval: 77 ± 18 {sd} days; range: 31-112 days). There was no significant bias in RDI between study nights using several different RDI definitions including RDI 3% and RDI 4% (apnea or hypopnea events associated with ≥4% O 2 desaturation). Variability between studies estimated using intraclass correlations (ICC) ranged from 0.77 to 0.81. For subjects with a RDI 3% <15, variability increased as a function of increasing RDI, but for those with a RDI 3% ≥15, variability was constant. Body mass index, SEff, gender, or age did not directly predict RDI variability. Using RDI 4% cutpoints of ≤5, ≤10 and ≤15 events per hour of sleep demonstrated that 79.1%, 85.7%, and 87.9% of subjects, respectively, had the same classification of SDB status on both nights of study. There also was no significant bias in sleep staging, sleep efficiency, or arousal index between studies. However, variability was greater with ICC values ranging from 0.37 (% time in REM) to 0.76 (arousal index). Conclusion: In the Sleep Heart Health Study, accurate estimates of the severity of sleep-disordered breathing and the quality of sleep were obtained from a single night of unattended nonlaboratory polysomnography. These findings may be applicable to other large epidemiologic studies provided that similar recording techniques and quality-assurance procedures are followed.
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影响因子：
5.6
作者：
Redline, S;Sanders, M
通讯作者：
Sanders, M
影响因子：
5.6
作者：
S. Quan;B. Howard;C. Iber;C. Iber;J. Kiley;F. Nieto;G. O'Connor;D. Rapoport;S. Redline;
通讯作者：
S. Quan;B. Howard;C. Iber;C. Iber;J. Kiley;F. Nieto;G. O'Connor;D. Rapoport;S. Redline;
影响因子：
5.6
作者：
S. Redline;M. Sanders;Bonnie K. Lind;S. Quan;C. Iber;D. Gottlieb;W. Bonekat;D. Rapoport;Philip L.
通讯作者：
S. Redline;M. Sanders;Bonnie K. Lind;S. Quan;C. Iber;D. Gottlieb;W. Bonekat;D. Rapoport;Philip L.
影响因子：
5.6
作者：
Whitney, CW;Gottlieb, DJ;Nieto, FJ
通讯作者：
Nieto, FJ
影响因子：
9.6
作者：
BLIWISE, DL;BENKERT, RE;INGHAM, RH
通讯作者：
INGHAM, RH