Distant relatives of severe acute respiratory syndrome coronavirus and close relatives of human coronavirus 229E in bats, Ghana.
Distant relatives of severe acute respiratory syndrome coronavirus and close relatives of human coronavirus 229E in bats, Ghana.
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DOI:
10.3201/eid1509.090224
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发表时间:
2009-09
影响因子:
11.8
通讯作者:
Drosten C
中科院分区:
文献类型:
--
作者:
Pfefferle S;Oppong S;Drexler JF;Gloza-Rausch F;Ipsen A;Seebens A;Müller MA;Annan A;Vallo P;Adu-Sarkodie Y;Kruppa TF;Drosten C
Hipposideros spp. bats harbor a coronavirus that shares common ancestry with human viruses. We tested 12 bat species in Ghana for coronavirus (CoV) RNA. The virus prevalence in insectivorous bats (n = 123) was 9.76%. CoV was not detected in 212 fecal samples from Eidolon helvum fruit bats. Leaf-nosed bats pertaining to Hipposideros ruber by morphology had group 1 and group 2 CoVs. Virus concentrations were <45,000 copies/100 mg of bat feces. The diversified group 1 CoV shared a common ancestor with the human common cold virus hCoV-229E but not with hCoV-NL63, disputing hypotheses of common human descent. The most recent common ancestor of hCoV-229E and GhanaBt-CoVGrp1 existed in ≈1686–1800 ad. The GhanaBt-CoVGrp2 shared an old ancestor (≈2,400 years) with the severe acute respiratory syndrome–like group of CoV.
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影响因子:
2.8
作者:
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通讯作者:
Kiefer, Andreas
影响因子:
11.8
作者:
Gloza-Rausch, Florian;Ipsen, Anne;Seebens, Antje;Goettsche, Matthias;Panning, Marcus;Drexler, Jan Felix;Petersen, Nadine;Annan, Augustina;Grywna, Klaus;Mueller, Marcel;Pfefferle, Susanne;Drosten, Christian
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影响因子:
9.8
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通讯作者:
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通讯作者:
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