Detection and prevalence patterns of group I coronaviruses in bats, northern Germany.

Detection and prevalence patterns of group I coronaviruses in bats, northern Germany.
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德国北部蝙蝠中I组冠状病毒的检测和患病率模式。

DOI:
10.3201/eid1404.071439
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发表时间:
2008-04
影响因子:
11.8
通讯作者:
Drosten, Christian
Drosten, Christian
中科院分区:
医学2区
文献类型:
--
作者:
Gloza-Rausch, Florian;Ipsen, Anne;Seebens, Antje;Goettsche, Matthias;Panning, Marcus;Drexler, Jan Felix;Petersen, Nadine;Annan, Augustina;Grywna, Klaus;Mueller, Marcel;Pfefferle, Susanne;Drosten, Christian

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该病毒可能通过繁殖和母婴传播维持在人群水平上。我们通过逆转录-PCR检测了来自北方德国7种不同蝙蝠的315只蝙蝠的冠状病毒。总患病率为9.8%。在4种蝙蝠(鼠耳蝠、鼠耳蝠、鼠耳蝠)中发现了4个I组冠状病毒谱系。道氏伏翼、纳氏伏翼、侏儒伏翼)。这些谱系形成了在德国北方发现的蝙蝠冠状病毒的单系分支。蝙蝠冠状病毒的分支与中国鼠耳蝠属的I型冠状病毒分支有姐妹关系。Ricketti)。年龄小和正在哺乳,而不是性别或现有的妊娠,与冠状病毒检测显着相关。该病毒可能是通过繁殖和传播在母体群体中维持的,而不是在个体蝙蝠中维持的。
The virus is probably maintained on the population level by amplification and transmission in maternity colonies. We tested 315 bats from 7 different bat species in northern Germany for coronaviruses by reverse transcription–PCR. The overall prevalence was 9.8%. There were 4 lineages of group I coronaviruses in association with 4 different species of verspertilionid bats (Myotis dasycneme, M. daubentonii, Pipistrellus nathusii, P. pygmaeus). The lineages formed a monophyletic clade of bat coronaviruses found in northern Germany. The clade of bat coronaviruses have a sister relationship with a clade of Chinese type I coronaviruses that were also associated with the Myotis genus (M. ricketti). Young age and ongoing lactation, but not sex or existing gravidity, correlated significantly with coronavirus detection. The virus is probably maintained on the population level by amplification and transmission in maternity colonies, rather than being maintained in individual bats.
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发表时间: 2003-11
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