Diet Quality Is Associated with Glucose Regulation in a Cohort of Young Adults.
Diet Quality Is Associated with Glucose Regulation in a Cohort of Young Adults.
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DOI：
10.3390/nu14183734
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发表时间：
2022-09-10
期刊：
影响因子：
5.9
通讯作者：
Chatzi L
中科院分区：
文献类型：
--
作者：
Costello E;Goodrich J;Patterson WB;Rock S;Li Y;Baumert B;Gilliland F;Goran MI;Chen Z;Alderete TL;Conti DV;Chatzi L
年轻发病的2型糖尿病和前驱糖尿病是一种日益流行的疾病。饮食不良是老年人T2D的已知危险因素，但饮食对T2D危险因素的贡献在年轻人中没有得到很好的描述。我们的目标是检查饮食质量与糖尿病前期、血糖调节和年轻人肥胖的关系。2014年至2018年对155名青壮年(n=155，年龄17-22岁)进行了检查，并于2020年至2022年对进行了随访。在每次访问中，参与者都完成了饮食和身体成分评估以及口服葡萄糖耐量测试。评估了四种饮食模式的依从性：控制高血压的饮食方法(DASH)、健康饮食指数(HEI)、地中海饮食和饮食炎症指数(DII)。回归分析被用来确定调整后的饮食与糖尿病前期和肥胖风险的相关性。随访期间DASH或HEI得分每增加1分，患糖尿病前期风险分别降低%(OR，95%CI：0.36，0.17~0.68)和9%(OR，95%CI：0.91，0.85~0.96)。DASH饮食与肥胖呈负相关，而DII与肥胖呈正相关。总而言之，HEI和DASH评分的积极变化与年轻人糖尿病前期风险的降低有关。
Young-onset type 2 diabetes and prediabetes is a growing epidemic. Poor diet is a known risk factor for T2D in older adults, but the contribution of diet to risk factors for T2D is not well-described in youth. Our objective was to examine the relationship of diet quality with prediabetes, glucose regulation, and adiposity in young adults. A cohort of young adults (n = 155, age 17–22) was examined between 2014–2018, and 89 underwent a follow-up visit from 2020–2022. At each visit, participants completed diet and body composition assessments and an oral glucose tolerance test. Adherence to four dietary patterns was assessed: Dietary Approaches to Stop Hypertension (DASH), Healthy Eating Index (HEI), Mediterranean diet, and Diet Inflammatory Index (DII). Regression analyses were used to determine adjusted associations of diet with risk for prediabetes and adiposity. Each one-point increase in DASH or HEI scores between visits reduced the risk for prediabetes at follow-up by 64% (OR, 95% CI: 0.36, 0.17–0.68) and 9% (OR, 95% CI: 0.91, 0.85–0.96), respectively. The DASH diet was inversely associated with adiposity, while DII was positively associated with adiposity. In summary, positive changes in HEI and DASH scores were associated with reduced risk for prediabetes in young adults.
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影响因子：
33.9
作者：
Divers, Jasmin;Mayer-Davis, Elizabeth J.;Wagenknecht, Lynne E.
通讯作者：
Wagenknecht, Lynne E.
饮食质量分数和男性2型糖尿病的风险。
影响因子：
16.2
作者：
de Koning L;Chiuve SE;Fung TT;Willett WC;Rimm EB;Hu FB
通讯作者：
Hu FB
影响因子：
6.1
作者：
Barnes, T. L.;Crandell, J. L.;Bell, R. A.;Mayer-Davis, E. J.;Dabelea, D.;Liese, A. D.
通讯作者：
Liese, A. D.
影响因子：
3.7
作者：
Esposito, Katherine;Chiodini, Paolo;Giugliano, Dario
通讯作者：
Giugliano, Dario
影响因子：
5.1
作者：
Cha E;Pasquel FJ;Yan F;Jacobs DR Jr;Dunbar SB;Umpierrez G;Choi Y;Shikany JM;Bancks MP;Reis JP;Spezia Faulkner M
通讯作者：
Spezia Faulkner M