Change in DASH diet score and cardiovascular risk factors in youth with type 1 and type 2 diabetes mellitus: The SEARCH for Diabetes in Youth Study.

Change in DASH diet score and cardiovascular risk factors in youth with type 1 and type 2 diabetes mellitus: The SEARCH for Diabetes in Youth Study.
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DOI:
10.1038/nutd.2013.32
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发表时间:
2013-10-14
影响因子:
6.1
通讯作者:
Liese, A. D.
Liese, A. D.
中科院分区:
医学2区
文献类型:
--
作者:
Barnes, T. L.;Crandell, J. L.;Bell, R. A.;Mayer-Davis, E. J.;Dabelea, D.;Liese, A. D.

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患有糖尿病的年轻人患心血管疾病(CVD)的风险增加。坚持饮食方法停止高血压(DASH)饮食已被证明可以改善CVD风险。在这项研究中,我们评估了以DASH为特征的饮食质量变化是否与糖尿病青年CVD危险因素随时间的变化相关。将纵向混合模型应用于青年糖尿病研究的797名参与者的数据,代表三个时间点:基线,12个月和60个月随访。数据仅限于2002-2005年首次诊断出糖尿病的青年。DASH相关的依从性较差,随着时间的推移变化很小。然而,DASH饮食评分的增加与1型糖尿病青年的HbA 1c水平降低(β=-0.20,P值=0.0063)和2型糖尿病青年的收缩压降低(β=-2.02,P值=0.0406)显著相关。改善饮食质量可能对1型或2型糖尿病患者有益。然而,在更大的1型和2型糖尿病青年群体中开展进一步的工作是可取的。
Youth with diabetes are at an increased risk of cardiovascular disease (CVD). Adherence to the Dietary Approaches to Stop Hypertension (DASH) diet has been shown to improve CVD risk. In this study, we evaluated whether changes in diet quality as characterized by DASH are associated with changes in CVD risk factors in youth with diabetes over time. Longitudinal mixed models were applied to data from 797 participants in the SEARCH for Diabetes in Youth Study representing three time points: baseline, 12- and 60-month follow-up. Data were restricted to youth whose diabetes was first diagnosed in 2002–2005. DASH-related adherence was poor and changed very little over time. However, an increase in DASH diet score was significantly associated with a decrease in HbA1c levels in youth with type 1 diabetes (β=−0.20, P-value=0.0063) and a decrease in systolic blood pressure among youth with type 2 diabetes (β=−2.02, P-value=0.0406). Improvements in dietary quality may be beneficial in youth with type 1 or type 2 diabetes. However, further work in larger groups of youth with type 1 and 2 diabetes is desirable.
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