Non-invasive brain stimulation in neurorehabilitation: local and distant effects for motor recovery.
Non-invasive brain stimulation in neurorehabilitation: local and distant effects for motor recovery.
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DOI：
10.3389/fnhum.2014.00378
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发表时间：
2014
影响因子：
2.9
通讯作者：
Cohen LG
中科院分区：
文献类型：
--
作者：
Liew SL;Santarnecchi E;Buch ER;Cohen LG
非侵入性脑刺激（NIBS）可以通过可塑性过程的因果诱导来促进神经损伤后的运动恢复。神经损伤，如中风，往往会导致严重的长期身体残疾，尽管强化治疗，大部分脑损伤幸存者未能恢复完全的运动功能。新兴的研究表明，NIBS技术，如经颅磁（TMS）和直流电（tDCS）刺激，与习惯使用的神经康复治疗，可以提高运动恢复。本文提供了一个一般性的审查TMS和tDCS的范例，他们的运作机制和刺激技术用于神经康复，特别是中风。TMS和tDCS影响刺激位置下的区域神经活动以及整个大脑的远程互连网络活动。我们讨论了最近的研究，记录NIBS对全球大脑活动的影响与各种神经影像学技术，这有助于表征更准确的NIBS刺激更好的策略。这些快速增长的调查领域可能会提高基于NIBS的临床康复干预措施的有效性。
Non-invasive brain stimulation (NIBS) may enhance motor recovery after neurological injury through the causal induction of plasticity processes. Neurological injury, such as stroke, often results in serious long-term physical disabilities, and despite intensive therapy, a large majority of brain injury survivors fail to regain full motor function. Emerging research suggests that NIBS techniques, such as transcranial magnetic (TMS) and direct current (tDCS) stimulation, in association with customarily used neurorehabilitative treatments, may enhance motor recovery. This paper provides a general review on TMS and tDCS paradigms, the mechanisms by which they operate and the stimulation techniques used in neurorehabilitation, specifically stroke. TMS and tDCS influence regional neural activity underlying the stimulation location and also distant interconnected network activity throughout the brain. We discuss recent studies that document NIBS effects on global brain activity measured with various neuroimaging techniques, which help to characterize better strategies for more accurate NIBS stimulation. These rapidly growing areas of inquiry may hold potential for improving the effectiveness of NIBS-based interventions for clinical rehabilitation.
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影响因子：
9.2
作者：
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通讯作者：
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影响因子：
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作者：
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影响因子：
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作者：
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影响因子：
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作者：
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通讯作者：
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影响因子：
64.8
作者：
Cohen, LG;Celnik, P;Hallett, M
通讯作者：
Hallett, M