Epigenetics for the social sciences: justice, embodiment, and inheritance in the postgenomic age

Epigenetics for the social sciences: justice, embodiment, and inheritance in the postgenomic age
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社会科学的表观遗传学:后基因组时代的正义、体现和继承

DOI:
10.1080/14636778.2015.1034850
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发表时间:
2015
影响因子:
1.8
通讯作者:
Maurizio Meloni
Maurizio Meloni
中科院分区:
医学4区
文献类型:
--
作者:
Maurizio Meloni

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在这篇论文中,我首先将当前对表观遗传学的兴趣上升放在了二十世纪生物学试图超越基因的更广泛的历史中。在第二部分,在总结了表观遗传突变和遗传突变之间的主要区别之后,我考虑了表观遗传突变的独特特征对社会科学可能产生的什么样的影响。我特别侧重于两个方面的调查:(A)正义理论中自然和社会不平等之间界限的模糊及其对公共政策和公共卫生的可能影响;(B)身体构成严重依赖于其物质和社会塑造的环境的观念的加深(“具体化建构主义”)。总而言之,我对表观遗传学在更广泛的社会中可能出现的一些(已知的和前所未有的)问题提出了一些警示性的思考。
In this paper, I firstly situate the current rise of interest in epigenetics in the broader history of attempts to go “beyond the gene” in twentieth-century biology. In the second part, after a summary of the main differences between epigenetic and genetic mutations, I consider what kind of implications the sui generis features of epigenetic mutations may have for the social sciences. I focus in particular on two sites of investigation: (a) the blurring of the boundaries between natural and social inequalities in theories of justice and their possible implications for public policy and public health and (b) a deepening of the notion that the constitution of the body is deeply dependent on its material and socially shaped surroundings (“embodied constructivism”). In conclusion, I advance some cautionary reflections on some of the (known and unprecedented) problems that the circulation of epigenetics in wider society may present.
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