Cognition, language, and clinical pathological features of non-Alzheimer's dementias: an overview.
Cognition, language, and clinical pathological features of non-Alzheimer's dementias: an overview.
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DOI：
10.1016/j.jcomdis.2010.04.011
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发表时间：
2010-09
影响因子：
1.7
通讯作者：
Neils-Strunjas, Jean
中科院分区：
文献类型：
--
作者：
Reilly, Jamie;Rodriguez, Amy D.;Lamy, Martine;Neils-Strunjas, Jean
有许多不同形式的痴呆症，其药理学和行为管理不同。痴呆变体的鉴别诊断目前依赖于遗传和蛋白质生物标志物、神经解剖学完整性和行为的加权组合。由于不同痴呆亚型的初始表现症状高度重叠，诊断特异性变得复杂。因此，可靠的标记物具有相当大的诊断价值。交流障碍已被证明是区分痴呆亚型的最强预测因子之一。因此，语言语言病理学家可能会对痴呆症的诊断和持续的管理做出越来越明显的贡献。然而，这种潜在贡献的价值和持久性需要一个关于不同痴呆变体的独特特征的改进的学科范围的知识基础。为此，我们概述了四种最常见的非阿尔茨海默氏痴呆症的认知、语言和临床病理特征：额颞叶痴呆、血管性痴呆、路易体病痴呆和帕金森病痴呆。
There are many distinct forms of dementia whose pharmacological and behavioral management differ. Differential diagnosis among the dementia variants currently relies upon a weighted combination of genetic and protein biomarkers, neuroanatomical integrity, and behavior. Diagnostic specificity is complicated by a high degree of overlap in the initial presenting symptoms across dementia subtypes. For this reason, reliable markers are of considerable diagnostic value. Communication disorders have proven to be among the strongest predictors for discriminating among dementia subtypes. As such, Speech-Language Pathologists may be poised to make an increasingly visible contribution to dementia diagnosis and its ongoing management. The value and durability of this potential contribution, however, demands an improved discipline-wide knowledge base about the unique features associated with different dementia variants. To this end we provide an overview of cognition, language, and clinical pathological features of four of the most common non-Alzheimer’s dementias: Frontotemporal Dementia, Vascular Dementia, Lewy Body Disease Dementia, and Parkinson’s Disease Dementia.
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影响因子：
11
作者：
BYRNE, EJ;LENNOX, G;GODWINAUSTEN, RB
通讯作者：
GODWINAUSTEN, RB
影响因子：
9.9
作者：
Ash, S;Moore, P;Grossman, M
通讯作者：
Grossman, M
影响因子：
9.9
作者：
Ballard, C.;Ziabreva, I.;Aarsland, D.
通讯作者：
Aarsland, D.
DOI：
10.1076/jcen.21.6.816.862
发表时间：
1999-12-01
影响因子：
2.2
作者：
Almkvist, O;Fratiglioni, L;Bäckman, L
通讯作者：
Bäckman, L
影响因子：
3.4
作者：
Blazely, AM;Coltheart, M;Casey, BJ
通讯作者：
Casey, BJ