Analysis of genetic systems using experimental evolution and whole-genome sequencing.
Analysis of genetic systems using experimental evolution and whole-genome sequencing.
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DOI:
10.1186/gb-2007-8-1-201
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发表时间:
2007
期刊:
影响因子:
12.3
通讯作者:
Kishony R
中科院分区:
文献类型:
--
作者:
Hegreness M;Kishony R
Whole-genome sequencing of bacteria evolving in the laboratory promises to reveal the complex network of mutations that underlie adaptation. The application of whole-genome sequencing to the study of microbial evolution promises to reveal the complex functional networks of mutations that underlie adaptation. A recent study of parallel evolution in populations of Escherichia coli shows how adaptation involves both functional changes to specific proteins as well as global changes in regulation.
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通讯作者:
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