Hispanic/Latino Acculturation Profiles and Telomere Length: Latent Class Analysis on a Nationally Representative Sample.
Hispanic/Latino Acculturation Profiles and Telomere Length: Latent Class Analysis on a Nationally Representative Sample.
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DOI：
10.3389/fpubh.2021.640226
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发表时间：
2021
影响因子：
5.2
通讯作者：
Williams F
中科院分区：
文献类型：
--
作者：
Montiel Ishino FA;McNab P;Villalobos K;Cohen JH;Nápoles AM;Williams F
背景：居住在美国的外国出生的拉美裔/拉美裔美国人的文化适应特征及其对端粒长度的影响相对未知。现有的有限研究将文化适应与端粒长度缩短联系在一起。目的：确定美国有代表性的拉美裔/拉丁裔样本中的文化适应特征，然后检查不同特征之间的端粒长度差异。方法：我们利用1999-2002年国民健康和营养检查调查(N=2,292)，对一个非制度化的具有美国代表性的拉美裔/拉丁裔样本进行了潜在类别分析。文化适应的潜在变量是通过在美国生活的时间长短和儿童时期使用的语言(即西班牙语和/或英语)来评估的，这些语言通常是在家里说的，用于思考，以及与朋友一起使用。以从白细胞中评估的端粒长度作为远端连续结果。结果：(1)低文化适应[33.2%样本]；(2)部分整合[18.6%样本]；(3)整合[19.4%样本]；(4)部分同化[15.1%样本]；(5)同化[13.7%样本]。文化适应档案显示，尽管在美国呆的时间很长，但条件概率与语言使用的细微差别。虽然端粒长度确实不同，但不同的图谱之间没有显著差异。结论：识别的图谱显示，可能的生活过程和世代影响可能在部分同化和同化图谱中起作用。我们的发现扩展了公共卫生研究，使用复杂的调查数据来识别和评估文化适应概况和健康生物标记物的动态关系，同时是第一批使用以人为中心的方法检查这一背景的人之一。
Background: Acculturation profiles and their impact on telomere length among foreign-born Hispanics/Latinos living in the United States (US) are relatively unknown. The limited research available has linked acculturation with shortened telomere length. Objectives: To identify acculturation profiles among a US representative sample of Hispanics/Latinos and to then examine telomere length differences between profiles. Methods: We conducted a latent class analysis among a non-institutionalized US-representative sample of Hispanics/Latinos using the 1999–2002 National Health and Nutrition Examination Survey (N = 2,292). The latent variable of acculturation was assessed by length of time in the US and language used as a child, read and spoken, usually spoken at home, used to think, and used with friends (i.e., Spanish and/or English). Telomere length assessed from leukocytes was used as the distal continuous outcome. Results: We identified five profiles: (1) low acculturated [33.2% of sample]; (2) partially integrated [18.6% of sample]; (3) integrated [19.4% of sample]; (4) partially assimilated [15.1% of sample]; and (5) assimilated [13.7% of sample]. Acculturation profiles revealed nuanced differences in conditional probabilities with language use despite the length of time spent in the US. While telomere length did vary, there were no significant differences between profiles. Conclusion: Profiles identified revealed that possible life-course and generational effects may be at play in the partially assimilated and assimilated profiles. Our findings expand public health research using complex survey data to identify and assess the dynamic relationship of acculturation profiles and health biomarkers, while being among the first to examine this context using a person-centered approach.
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DOI：
10.1158/1055-9965.epi-09-0238
发表时间：
2009-07
期刊：
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
影响因子：
--
作者：
Hamilton AS;Hofer TP;Hawley ST;Morrell D;Leventhal M;Deapen D;Salem B;Katz SJ
通讯作者：
Katz SJ
DOI：
10.1016/j.socscimed.2017.01.029
发表时间：
2017-03
期刊：
Social science & medicine (1982)
影响因子：
--
作者：
Fox M;Thayer Z;Wadhwa PD
通讯作者：
Wadhwa PD
影响因子：
5
作者：
Geronimus AT;Pearson JA;Linnenbringer E;Schulz AJ;Reyes AG;Epel ES;Lin J;Blackburn EH
通讯作者：
Blackburn EH
影响因子：
2.1
作者：
Giuntella, Osea;Stella, Luca
通讯作者：
Stella, Luca
影响因子：
5.4
作者：
Abraído-Lanza, AF;Chao, MT;Flórez, KR
通讯作者：
Flórez, KR